释 义 n. [生化] 神经降压素
短 语 neurotensin receptor 神经降压素受体
neurotensin assay 神经降压素测定
例 句 Our findings suggest that curcumin may be useful for colon cancer treatment, as well as potentialcolon cancer suppression, in cells that respond to this gastrointestinal hormone, neurotensin. 我们的发现表明黄素可能对治疗结肠癌很有用，同时在对胃肠激素神经降压素起反应的细胞内对结肠癌有潜在的抑制作用。
作者： Thomas Langbein
期刊：J Nucl Med
Molecular alterations in malignant disease result in the expression or upregulations of various targets that can be used for imaging and treatment with radiopharmaceuticals. This theranostic principle has acquired greater importance in personalized medicine in recent years, particularly in oncology, where advanced tumors can be treated effectively with low side effects. Since the pioneering use of I in differentiated thyroid cancer in the 1940s, remarkable achievements in nuclear medicine endoradiotherapy have been demonstrated, mainly in the treatment of neuroendocrine neoplasms by using Lu-labeled somatostatin analogs or in the treatment of advanced prostate cancer using prostate-specific membrane antigen-directed radionuclide therapy. Besides that, this review focuses on promising novel radiopharmaceuticals and describes their preclinical and clinical status. Radiolabeled antibodies, such as I-omburtamab directed against the B7-H3 protein on the surface of neuroblastoma cells; HuMab-5B1, a Zr/Lu-labeled antibody for the treatment of CA19-9-expressing malignancies; and Lu-lilotomab, a CD37 antibody for the treatment of B-cell lymphomas, are being highlighted. The neurotensin receptor ligand In/Lu-3B-227 has demonstrated high potential in imaging and therapy for several malignancies (e.g., pancreatic adenocarcinomas).