释 义 n. [外科] 多肌炎
短 语 idiopathic polymyositis 特发性多发性肌炎
例 句 Analysing the data of the clinical manifestations, biochemical tests, electromyographes andmuscular biopsies, the authors proposed the diagnostic criteria of polymyositis anddermatomyositis. 从临床表现、生化检查、肌电图及肌肉活检等方面进行分析，提出多发性肌炎与皮肌炎的诊断条件。
作者： Sandrine Herbelet
Dermatomyositis (DM), polymyositis (PM), inclusion body myositis (IBM), immune mediated necrotizing myopathy (IMNM) and overlap myositis (OM) are classified as inflammatory myopathies (IM) with involvement of autoimmune features such as autoreactive lymphocytes and autoantibodies. Autoimmunity can be defined as a loss in self-tolerance and attack of autoantigens by the immune system. Self-tolerance is achieved by a group of immune mechanisms occurring in central and periphal lymphoid organs and tissues, called immune checkpoints, that work in synergy to protect the body from harmful immune reactions. Autoimmune disorders appear when immune checkpoints fail. In this review, the different immune checkpoint failures are discussed in DM, PM, IBM and IMNM. Exploring research contribution in each of these immune checkpoints might help to highlight research perspectives in the field and obtain a more complete picture of IM disease pathology.