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首页 > 医学词汇大全 > Syringomyelia
Syringomyelia

神经

关键词神经 疾病 脊髓疾病

词汇介绍

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解析

syringomyelia  英 [sɪ,rɪŋgə(ʊ)maɪ'iːlɪə]  美 

释    义   n. [内科] 脊髓空洞症

       traumatic syringomyelia 外伤后脊髓空洞症

例    句   Objective : To analyze MRI manifestations of post-traumatic syringomyelia and its formation mechanism. 目的:分析创伤后脊髓空洞症的MRI表现及其形成机制。

概述

脊髓空洞症是一种慢性进行性脊髓疾病,病变多位于颈髓,也可累及延髓,称为延髓空洞症。脊髓空洞症与延髓空洞症可单独发生或并发,典型临床表现为节段性分离性感觉障碍、病变节段支配区肌萎缩及营养障碍等。病因及发病机制①先天性发育异常。本病常合并小脑扁桃体下疝、脊柱裂、脑积水、颈肋、弓形足等畸形,故认为脊髓空洞症是脊髓先天性发育异常。有人认为是由于胚胎期脊髓神经管闭合不全或脊髓内先天性神经胶质增生导致脊髓中心变性所致。②血液循环异常。颈枕区先天性异常影响脑脊液自第四脑室进入蛛网膜下腔,脑室压力搏动性增高

Origin of Syrinx Fluid in Syringomyelia: A Physiological Study复制标题

脊髓空洞症患者脑脊液来源的生理学研究

发表时间:2019-02-01

影响因子:4.6

作者: John D Heiss

期刊:Neurosurgery

BACKGROUND: The origin of syrinx fluid is controversial. OBJECTIVE: To elucidate the mechanisms of syringomyelia associated with cerebrospinal fluid pathway obstruction and with intramedullary tumors, contrast transport from the spinal subarachnoid space (SAS) to syrinx was evaluated in syringomyelia patients.METHODS: We prospectively studied patients with syringomyelia: 22 with Chiari I malformation and 16 with SAS obstruction-related syringomyelia before and 1 wk after surgery, and 9 with tumor-related syringomyelia before surgery only. Computed tomography-myelography quantified dye transport into the syrinx before and 0.5, 2, 4, 6, 8, 10, and 22 h after contrast injection by measuring contrast density in Hounsfield units (HU). RESULTS: Before surgery, more contrast passed into the syrinx in Chiari I malformation-related syringomyelia and spinal obstruction-related syringomyelia than in tumor-related syringomyelia, as measured by (1) maximum syrinx HU, (2) area under the syrinx concentration-time curve (HU AUC), (3) ratio of syrinx HU to subarachnoid cerebrospinal fluid (CSF; SAS) HU, and (4) AUC syrinx/AUC SAS. More contrast (AUC) accumulated in the syrinx and subarachnoid space before than after surgery.

译文

背景:syrinx液的起源是有争议的。目的:为了阐明脊髓空洞症与脑脊液通路梗阻和髓内肿瘤相关的机制,在脊髓空洞症患者中评估脊髓蛛网膜下腔(SAS)与syrinx的对比转运。方法:前瞻性研究脊髓空洞症患者:其中Chiari I畸形22例,术前1周和术后1周出现SAS梗阻相关性脊髓空洞症16例,术前仅有9例肿瘤相关性脊髓空洞症。计算机断层扫描 - 脊髓造影术通过测量Hounsfield单位(HU)中的对比密度,在造影剂注射前和注射后0.5,2,4,6,8,10和22小时量化染料转运到注射器中。结果:在手术前,Chiari I畸形相关的脊髓空洞症和脊髓梗阻相关的脊髓空洞症中的syrinx与肿瘤相关的脊髓空洞症相比,通过(1)最大的syrinx HU,(2)syrinx浓度下的面积测量 - 时间曲线(HU AUC),(3)syrinx HU与蛛网膜下腔脑脊液(CSF; SAS)HU的比率,和(4)AUC syrinx / AUC SAS。在手术前和手术后积累的更多对比度(AUC)累积在睫状体和蛛网膜下腔。