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首页 > 医学词汇大全 > Status Epilepticus
Status Epilepticus

神经

关键词神经 临床研究术语 癫痫

词汇介绍

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解析

status   英 ['steɪtəs]   [ˈstetəs] 

        n. 地位;状态;情形;重要身分

        Talent: there as only status.  人才观: 有作为,才有地位。

 

epileptic   英 [,epɪ'leptɪk]   [,ɛpə'lɛptɪk] 

        adj. 患癫痫的;癫痫引起的

   n. 癫痫病患者

同根词    epilepsy n. [内科] 癫痫,癫痫症

        People cried that new sorts of light would give them migraine and epileptic fits. 人们喊着新品种的电灯会引起他们偏头痛和癫痫发作。

概述

癫痫持续状态(SE)是一种以持续的癫痫发作为特征的病理状况,为神经科的急症,一旦发作就应该紧急处理。既往国内沿用的定义为出现两次以上的癫痫发作,而在发作间期意识未完全恢复;或者一次癫痫发作持续30分钟以上。目前,基于癫痫持续状态的临床控制和对脑的保护,提出临床上更为实用的定义为:一次发作没有停止,持续时间大大超过了具有该型癫痫的大多数患者的发作时间;或反复的发作,在发作间期患者的意识状态不能恢复到基线期水平。分类(1)全面性癫痫持续状态:全面性强直一阵挛癫痫持续状态、阵挛性癫痫持续状态、失神

The difficulty of diagnosing NCSE in clinical practice; external validation of the Salzburg criteria复制标题

临床实践中诊断NCSE的困难; 萨尔茨堡标准的外部验证

发表时间:2019-07-18

影响因子:5.6

作者: Rianne J. M. Goselink

期刊:Epilepsia

To improve the diagnostic accuracy of electroencephalography (EEG) criteria for nonconvulsive status epilepticus (NCSE), external validation of the recently proposed Salzburg criteria is paramount. We performed an external, retrospective, diagnostic accuracy study of the Salzburg criteria, using EEG recordings from patients with and without a clinical suspicion of having NCSE. Of the 191 EEG recordings, 12 (12%) was classified as an NCSE according to the reference standard. In the validation cohort, sensitivity was 67% and specificity was 89%. The positive predictive value was 47% and the negative predictive value was 95%. Ten patients in the control group (n = 93) were false positive, resulting in a specificity of 89.2%. The interrater agreement between the reference standards and between the scorers of the Salzburg criteria was moderate; disagreement occurred mainly in patients with an epileptic encephalopathy. The Salzburg criteria showed a lower diagnostic accuracy in our external validation study than in the original design, suggesting that they cannot replace the current practice of careful weighing of both clinical and EEG information on an individual basis.

译文

为了提高非惊厥性癫痫持续状态(NCSE)的脑电图(EEG)标准的诊断准确性,最近提出的萨尔茨堡标准的外部验证是至关重要的。我们使用来自患者的EEG记录进行了萨尔茨堡标准的外部,回顾性和诊断准确性研究,该患者有或没有临床怀疑患有NCSE。在191份EEG录音中,12份(12%)根据参考标准被归类为NCSE。在验证队列中,灵敏度为67%,特异性为89%。阳性预测值为47%,阴性预测值为95%。对照组(n = 93)的10名患者为假阳性,特异性为89.2%。参考标准与萨尔茨堡标准的得分者之间的评估协议是适度的;分歧主要发生在癫痫性脑病患者身上。萨尔茨堡标准显示我们的外部验证研究的诊断准确性低于原始设计,这表明它们无法取代目前在个体基础上仔细权衡临床和EEG信息的做法。