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首页 > 医学词汇大全 > Laser Ablation
Laser Ablation

神经

关键词神经 治疗方法 外科治疗

词汇介绍

拓展阅读

解析

laser    英 ['leɪzə]   ['lezɚ] 

        n. 激光  

  n. (Laser)人名;()拉泽

       laser rangefinder 激光测距仪雷射测距仪激光测距机激光测距

   laser linewidth 激光谱线宽度雷射光谱线宽[激光激光线宽激光束宽

   laser pumping [激光激光泵浦激光激励 [激光激光抽运

       How do I set a laser printer to stun?  我怎么把一台激光打印机设置到震惊?

 

ablation     [ə'bleɪʃ(ə)n]   [ə'bleʃən] 

        n. [水文] 消融;切除

同根词    ablative adj. 离格的;消融的

ablative n. 烧蚀材料;离格

ablate vi. 脱落

ablate vt. 烧蚀;切除;使脱落

        However the energy and efficacy of ablation remain the major factors restricting the success rate. 然而,消融的能量和效能仍然是制约成功率的主要因素。 

概述

激光是处于低能级的原子基态,受到辐射后而激发到高能级状态发出的光。激光消融治疗按其应用方法分为间质激光凝固(ILD)和经腔隙激光热治疗(LITT)。原理激光治疗机理:发光现象是光源系统中的原子、分子、离子内部的能量变化的结果。激光照射产生的生物学效应是光的能量转换(1)光效应:组织吸收了激光的光量子后,可产生光化学反应、光电效应、电子跃迁、产生热量、造成组织电离分解产生自由基等变化,导致组织细胞损伤。(2)热效应:激光的本质是电磁波,在与组织的分子振动频率相同或相近时,可发生分子的谐振而产生

Gadolinium Deposition in the Brain in a Large Animal Model Comparison of Linear and Macrocyclic Gadolinium-Based Contrast Agents复制标题

大动物模型脑内钆沉积线性和大循环钆造影剂的比较

发表时间:2019-01-26

影响因子:6.1

作者: Alexander Radbruch

期刊:INVEST RADIOL

OBJECTIVE: Recent studies reported a signal intensity increase in the deep cerebellar nuclei (DCN) on magnetic resonance images caused by gadolinium deposition after the injection of gadolinium-based contrast agents (GBCAs). There is an ongoing debate if the propensity of a GBCA to deposit gadolinium is primarily determined by its class as either linear or macrocyclic. In the current study, we aimed to compare the amount and the distribution of retained gadolinium of linear and macrocyclic GBCAs in the DCN after a single injection at a dose comparable to a human patient's in a large animal model.MATERIALS AND METHODS: Eighteen sheep were randomly assigned in 6 groups of 3 animals, which received a single injection of 0.1 mmol/kg body weight of either the macrocyclic GBCAs gadobutrol, gadoteridol, or gadoterate meglumine; the linear GBCAs gadobenate dimeglumine or gadodiamide; or saline. Animals were euthanized 10 weeks after injection. Local distribution and concentration of gadolinium and colocalization to other metals (iron, zinc, copper) in the DCN was assessed by laser ablation-inductively coupled plasma-mass spectrometry.

译文

目的:最近的研究报告注射钆造影剂(GBCA)后钆沉积引起的磁共振图像中深小脑核(DCN)的信号强度增加。如果GBCA沉积钆的倾向主要由其类别确定为线性或大环,则一直存在争议。在目前的研究中,我们的目的是比较单次注射后DCN中线性和大环GBCA的保留钆的量和分布,其剂量与大型动物模型中的人类患者相当。材料与方法:18只羊随机分为6组,每组3只,每次注射0.1mmol / kg体重的大环GBCA钆钆,钆特醇或钆降葡甲胺;线性GBCA钆钆二甲基葡胺或钆双胺;或生理盐水。注射后10周对动物实施安乐死。通过激光烧蚀 - 电感耦合等离子体质谱法评估钆的局部分布和浓度以及与DCN中的其他金属(铁,锌,铜)的共定位。