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首页 > 医学词汇大全 > Iodixanol
Iodixanol

神经

关键词神经 治疗药物 造影剂

词汇介绍

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解析

iodixanol

释    义   碘克沙醇

例    句   Conclusions: The rate of CIN in high risk pts undergoing cardiac angiography is comparable after administration of iopamidol-370 or iodixanol-320. 结论: 使用碘帕醇-370或碘克沙醇-320后,接受心血管造影术的高危患者中CIN发生率是相当的。

概述

碘克沙醇为非离子型等渗碘造影剂,具有不解离、不带电荷、渗透压低及血浆等渗等优点,较其他离子型及非离子型的碘造影剂不良反应发生率低,由于其安全性高,受到临床的广泛亲睐,也是高敏体质的首选药。据katayama 等报告,在日本一项涉及337 647 例样本的临床试验中,非离子型造影剂组的严重过敏反应发生率仅为0.04%。指征和剂量DSA数字减影:造影剂可根据情况适当稀释。剂量根据造影的部位而定,可用5~60 ml/次,呵多次造影,但总剂量不宜超过2 ml/kg。CT增强扫描:用于全身各系统和各脏

Iodixanol versus Iopromide at Coronary CT Angiography: Lumen Opacification and Effect on Heart Rhythm-the Randomized IsoCOR Trial复制标题

碘克沙醇与碘普罗胺的冠状动脉CT血管造影: 管腔混浊和对心律的影响-随机IsoCOR试验

发表时间:2018-01-15

影响因子:7.6

作者: Marisa M Lubbers

期刊:Radiology

Purpose To show that equal coronary lumen opacification can be achieved with iso- and low-osmolar contrast media when it is injected at the same iodine delivery rate with contemporary cardiac computed tomographic (CT) protocols and to investigate the cardiovascular effect of iso-osmolar contrast media and the image quality achieved. Materials and Methods Institutional review board approval and written informed consent were obtained for the Effect of Iso-osmolar Contrast Medium on Coronary Opacification and Heart Rhythm in Coronary CT Angiography, or IsoCOR, trial. Between November 2015 and August 2016, 306 patients (167 [55%] women) at least 18 years old (weight range, 50-125 kg), were prospectively randomized to receive iso-osmolar iodixanol 270 or low-osmolar iopromide 300 contrast media. All coronary segments were assessed for intraluminal opacification and image quality and were compared by using the Student t test. Heart rate, arrhythmia, patient discomfort, and adverse events also were monitored.

译文

目的探讨等渗造影剂与低渗造影剂在同一碘输注率下,应用现代心脏ct(cardiac computed tomographic,ct)技术可获得相同的冠状动脉腔内混浊,并探讨等渗造影剂的心血管效应及成像质量。材料与方法在冠状动脉ct血管造影(isocor)试验中,等渗造影剂对冠状动脉混浊和心律的影响获得机构审查委员会的批准和书面知情同意。在2015年11月至2016年8月期间,306名至少18岁(体重范围50-125公斤)的患者(167名[55%]女性)前瞻性随机接受异渗透碘丙醇270或低渗透碘普罗胺300造影剂。对所有冠状动脉段进行腔内混浊和图像质量评估,并用student t检验进行比较。同时监测心率、心律失常、病人不适和不良事件。