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首页 > 医学词汇大全 > Chronic sclerosing sialadenitis
Chronic sclerosing sialadenitis

免疫

关键词免疫 疾病 慢性硬化性涎腺炎

词汇介绍

拓展阅读

解析

chronic  英  /ˈkrɒnɪk/  美  /ˈkrɑːnɪk/

释    义   adj. 慢性的;长期的;习惯性的

例    句   He was suffering from chronic bronchitis.他患有慢性支气管炎。

 

sclerosing  英  /skliə'rəusiŋ/  美  /skliə'rəusiŋ/

释    义   adj. 致硬化的,硬化型的;

               v. (使)硬化,引起……的硬化(sclerose的现在分词形式)

例    句   Subacute sclerosing panencephalitis (SSPE) is a very rare, progressive neurological disorder.亚急性硬化性全脑炎(SSPE)是一种十分罕见的进行性的神经疾患。

 

sialadenitis  英  /'saiə,lædə'naitis/  美  /'saiə,lædə'naitis/

释    义   n. [口腔] 涎腺炎

例    句   There were 6 complications (18%), including sialadenitis (4), gastrointestinal bleeding (1), and dehydration (1) after the procedure.手术后共有6个并发症18%,包括涎腺炎4,胃肠道出血1,脱水1。

概述

  慢性硬化性涎腺炎(CSS)是一种常累及单侧或双侧下颌下腺,表现为坚韧的痛或无痛性肿块的慢性涎腺炎症,多发于成年男性。其病机可能与基因易患性和异常免疫反应有关。实验室检查示IgG4升高。CSS特异性的病理组织学改变为富含细胞的纤维组织增生,形成具有明显不规则形状生发中心的淋巴滤泡。   发病机制   迄今有关CSS的发病机制分别有水电解质阻塞、涎石阻塞以及患者自身免疫性疾病等学说,但均未能明确地诠释其发病机制。近来,越

Sclerosing sialadenitis of the submandibular gland is rarely an immunoglobulin G4-related disease in the Finnish population.复制标题

在芬兰人群中,颌下腺硬化性涎腺炎很少是一种免疫球蛋白G4-related。

发表时间:2020-04-03

影响因子:6.0

作者: Peuraharju E

期刊:Mod Pathol

Chronic sclerosing sialadenitis may represent one of many manifestations of an immunoglobulin G4-related disease. However, existing studies typically consist of small patient cohorts rarely conducted in Western populations. The clinical behavior of chronic sclerosing sialadenitis, including follow-up data, warrants further study. Thus, we aimed to determine whether chronic sclerosing sialadenitis always presents as IgG4-related disease or associates with autoimmune diseases and to determine which additional examinations patients may require. Between 2000 and 2017, 51 patients undergoing submandibular gland resection within the Helsinki University Hospital area were diagnosed with chronic sclerosing sialadenitis. We re-evaluated all specimens and performed immunostaining for IgG4. IgG and CD31 stainings were performed for IgG4-positive specimens. IgG4-related disease diagnosis was defined by the Boston consensus statement criteria. We revised clinical data, distributing a follow-up questionnaire to patients to register symptoms of IgG4-related disease or autoimmune disease during follow-up.

译文

慢性硬化性涎腺炎可能是免疫球蛋白g4相关疾病的多种表现之一。然而,现有的研究通常包括小患者组,很少在西方人群中进行。慢性硬化性涎腺炎的临床表现,包括随访数据,值得进一步研究。因此,我们旨在确定慢性硬化性涎腺炎是否总是以igg4相关疾病或与自身免疫性疾病相关,并确定患者可能需要哪些额外检查。2000年至2017年,赫尔辛基大学医院区内51名接受颌下腺切除术的患者被诊断为慢性硬化性涎腺炎。我们重新评估所有标本并对IgG4进行免疫染色。对igg4阳性标本进行IgG和CD31染色。igg4相关疾病的诊断依据波士顿共识声明标准。我们修订了临床资料,向患者发放随访问卷,在随访期间记录igg4相关疾病或自身免疫性疾病的症状。