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首页 > 医学词汇大全 > polysaccharide of atractylodes macrocephala (PAM)
polysaccharide of atractylodes macrocephala (PAM)

免疫

关键词免疫 药物 白术多糖

词汇介绍

拓展阅读

解析

polysaccharide  英  /,pɒlɪ'sækəraɪd/  美  /,pɔli'sækəraid, -rid/

释    义   n. [有化] 多糖;多聚糖(等于polysaccharid)

例    句   The property of polysaccharide gums in Gleditsia sinensis Lam is studied.对皂荚的多糖胶性质进行了研究。

 

atractylodes

释    义   苍术属;苍术

例    句   The differentiation of commodities of Atractylodes reflected the unity and dialectical law, which is embodied in its clinical application.白术与苍术的商品分化是术属植物临床应用的具体体现,反映了统一性与辨证观。

 

macrocephala

释    义   白术;大头毛鳞菊

例    句   Serum containing Semen Arecae, Dandelion, Semen raphani and Atractylodes macrocephala can make notable contraction on colonic smooth muscle cells in rats.不同浓度槟榔、蒲公英、莱菔子、生白术中药血清均可引起结肠平滑肌细胞有效收缩。

概述

  白术多糖(PAM)是白术发挥其免疫促进作用的重要活性成分,PAM主要成分为甘露聚糖和果聚糖,两者约占总量的70%,现代药理学研究证实,PAM具有明显的免疫增强作用,具有天然性、多能性、协调性、无毒无抗等特点。   PAM对免疫功能的影响   1.对体液免疚的调节作用   机体的体液免疫功能是通过B淋巴细胞增殖分化产生抗体来完成的,机体血清中抗体水平高低位评估其免疫状况的重要指标之一。许多中药单品

Comparison of byakujutsu (Atractylodes rhizome) and sojutsu (Atractylodes lancea rhizome) on anti-inflammatory and immunostimulative effects in vitro.复制标题

Byakujutsu (白术) 和sojutsu (苍术) 体外抗炎和免疫刺激作用的比较。

发表时间:2018-01-07

影响因子:2.0

作者: Shimato Y

期刊:J Nat Med

The Japanese Pharmacopoeia defines byakujutsu (Atractylodes rhizome) as the rhizome of Atractylodes japonica or A. macrocephala and sojutsu (Atractylodes lancea rhizome) as the rhizome of A. lancea, A. chinensis, or their interspecific hybrids. Because their pharmaceutical uses differ in traditional Japanese Kampo medicine and traditional Chinese medicine, with less apparent scientific evidence, we compared the pharmacological properties between byakujutsu and sojutsu. Crude drug specimens of byakujutsu (n = 40) and sojutsu (n = 49) obtained in markets were identified by their species using DNA profiling. Their pharmacological properties were evaluated by the inhibitory effect of a MeOH extract of the samples on nitric oxide (NO) production by lipopolysaccharide-stimulated murine macrophage-like RAW264.7 cells and by the inducing effect of boiling water extract of the samples on granulocyte-colony stimulating factor (G-CSF) secretion from murine normal colonic epithelial MCE301 cells. We authenticated A. macrocephala (n = 8), A. japonica (n = 35), and the hybrid between A. macrocephala and A. japonica (n = 1), and they were used as byakujutsu.

译文

摘要《日本药典》将苍术(Atractylodes rhizome)定义为日本苍术(Atractylodes lancea rhizome)或苍术(Atractylodes lancea rhizome)的根茎。由于它们在日本传统堪布医学和中国传统医学中的药物用途不同,缺乏明显的科学证据,我们比较了拜日式和拜日式的药理特性。通过DNA图谱分析,鉴定了市场上获得的40株仙子和49株仙子的药材。药理性能进行评估的甲醇提取物的抑制作用对一氧化氮(NO)生产的样品lipopolysaccharide-stimulated鼠macrophage-like RAW264.7细胞和诱导效应的沸水提取样本的粒细胞集落刺激因子(g - csf)从小鼠正常结肠上皮MCE301细胞分泌。我们鉴定了大头鲂(n = 8)、粳稻(n = 35)和大头鲂与粳稻(n = 1)的杂交种,并将它们作为芥菜。