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首页 > 医学词汇大全 > Monoclonal gammopathies (MGP)
Monoclonal gammopathies (MGP)

免疫

关键词免疫 疾病 单克隆免疫球蛋白病

词汇介绍

拓展阅读

解析

monoclonal  英  /,mɒnə(ʊ)'kləʊn(ə)l/  美  /,mɑno'klonəl/

释    义   adj. 单克隆的;单细胞繁殖的

例    句   Results indicated that 4 monoclonal antibodies all have cross-reactions with Aspergillus terreus and Aspergillus niger.结果显示4株单抗与土曲霉、黑曲霉均有交叉反应。

 

gammopathy  英  /'ɡæməpθɪ/  美  /'ɡæməpθɪ/

释    义   n. 丙种球蛋白病

例    句   This was also true in comparison with patients with monoclonal gammopathies of undetermined significance.与意义未明的单克隆免疫球蛋白血症相比也同样升高。

概述

  单克隆免疫球蛋白病由一组异质性疾病组成,其特征在于B淋巴细胞或浆细胞克隆性增殖产生免疫球蛋白。大多数患者血液或尿液中可检测到单克隆免疫球蛋白。   单克隆免疫球蛋白相关肾损害   1.单克隆免疫球蛋白沉积病MIDD   MIDD主要分为轻链沉积病(LCDD),轻重链沉积病(LHCDD)以及重链沉积病(HCDD)。MIDD相关肾损害主要见于意义未明的单克隆免疫球蛋白病(MGUS)(

Monoclonal gammopathies: Electronic subspecialty consultation.复制标题

单克隆抗体病: 电子亚专科会诊。

发表时间:2018-04-10

影响因子:2.2

作者: Burwick N

期刊:Eur J Haematol

Electronic consultation (e-consult) is an important component of care for patients in the Veterans Health Administration who require subspecialty consultation but not urgent face-to-face evaluation. Monoclonal gammopathy of undetermined significance (MGUS) is a common reason for e-consult. While often benign, MGUS requires careful evaluation and persistent surveillance over time.To identify areas to improve MGUS care delivery by e-consult. We performed a retrospective review of our e-consult database and identified a cohort of 152 MGUS patients triaged for e-consult over a 5-year period (2010-2014). The median time to completion of an e-consult was 2 days. Ninety-six percent of MGUS e-consults had a hemoglobin >10 g/dL, and 90% had a creatinine <2 mg/dL. While the majority of e-consults were low risk, paraprotein surveillance varied over time and tracked with consult utilization. With a median follow-up of 44 months, there were 6 documented progression events, representing a mean rate of progression of 1% per year.

译文

电子会诊(e-consult)是退伍军人健康管理中需要亚专科会诊但不需要紧急面对面评估的病人护理的一个重要组成部分。未确定意义的单克隆性gammopathy (MGUS)是电子咨询的常见原因。MGUS通常是良性的,但需要仔细的评估和长期的监测。通过电子咨询来确定改善MGUS护理服务的领域。我们回顾了我们的电子咨询数据库,确定了152例MGUS患者,这些患者在5年(2010-2014年)的时间里进行了电子咨询。完成电子咨询的平均时间为2天。96%的MGUS -consults血红蛋白>10 g/dL, 90%的肌酐<2 mg/dL。虽然大多数电子咨询是低风险的,但副蛋白监测随时间而变化,并随着咨询的使用而跟踪。中位随访44个月,有6个记录的进展事件,平均进展率为每年1%。