Latent genital tuberculosis adversely affects the ovarian reserve in infertile women.复制标题

潜在生殖器结核对不孕妇女的卵巢储备产生不利影响。

Tuberculosis (TB), an infectious disease caused by Mycobacterium TB (M TB), is a major health issue of global importance. Six countries including India and China account for 60% of global TB burden and the incidence of TB is increasing even in low burden countries. Genital TB(GTB) is a common form of extrapulmonary TB secondary to haematogenous spread of the bacteria and is an important cause of infertility in women. The Fallopian tubes are the most commonly affected site, followed by the endometrium and ovaries. Infertility may be the only symptom in majority of the women with latent GTB. GTB is paucibacillary in nature, with a low detection rate (7–19%) when the common diagnostic modalities of microbiological culture, histopathology and laparoscopy are used in infertile women with clinical suspicion. In addition, an important feature of latent TB is loss of culturability . Both factors may contribute to the reported discordance in the detection rate between bacteriological culture and DNA PCR.

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