摘要

42 subfertile patients with normal levels of plasma testerone (26 subnormal, suffering from oligospermia) have been treated with a combination of clomiphene citrate (50 mg Clomid daily) and mesterolon (50 mg Proviron daily) over a period of at least 3-6 months. The treatment resulted in pregnancy in 6 cases and in a significant improvement of the sperm count in 16. In 7, however, whilst the sperm count improved the qualitative results were unsatisfactory as many sperms were immature. Restricted spermatogenesis and a sperm count below 5 million/ml must be considered unfavourable but does not constitute a counter-indication to the combined therapy. No hazardous complications were observed.

译文

42 名血浆孕酮水平正常的亚育患者 (26 名亚正常,患有少精症) 已经接受了克罗米芬 (每天 50 mg Clomid) 和麦斯托隆 (每天 50 mg Proviron) 的联合治疗在至少 3-6 个月的时间里。治疗导致 6 例妊娠,16 例精子数量显著改善。然而,在 7 年,虽然精子数量有所提高,但由于许多精子不成熟,定性结果并不令人满意。限制精子发生和精子数量低于 500万个/毫升必须被认为是不利的,但不构成联合疗法的相反指征。未观察到危险的并发症。

clomiphene citrate

妇产 促排卵 药物
概述  :  

社会的快速发展,导致诸如水、食物、空气等质量受到影响,越来越多的人开始患上不孕不育症。不孕不育症情况复杂,有些是因为男性的原因,有些则是因为女性的原因。治疗不孕不育症需要根据病情来决定,药物是重要的解决手段,氯米芬具有较强的抗雌激素作用和较弱的雌激素活性临床上主要用于避孕药引起的闭经及月经紊乱,是解决排卵的女性不育症中经常用到的药物。 适应证与禁忌证使用氯米芬的适应症为1)治疗无排卵的女性不育症,适用于体内有一定雌激素水平者;2)治疗黄体功能不足;3)测试卵巢功能;4)探测男性下丘

clomiphene  英 ['klɒməfi:n] 美 ['kloʊməfin]

释    义   n. 克罗米酚,舒经酚(一种合成的助生育药)

例    句   The most commonly prescribed ovulation drug is clomiphene citrate ( CC ). 最常用的排卵药是克罗米酚 ( CC )。

 

citrate  英 ['sɪtreɪt] 美 ['sɪtreɪt]

释    义   n. 柠檬酸盐

例    句   Levels of serum estradiol and progesterone were statistically significantly higher in the clomiphene citrate group. 在克罗米芬治疗组,血清雌激素和孕酮的水平明显升高。

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