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hyperprolactinemia

妇产

关键词妇产 疾病 生殖内分泌疾病

词汇介绍

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解析

hyperprolactinemia  

释    义   高催乳素血症;高泌乳激素血症;高泌乳素血症;催乳素过高血症

例    句   Hyperprolactinemia is mainly related with dysfunctional liver, spleen and kidney. 高泌乳素血症的发生主要与肝、脾、肾三脏功能失调有关。

概述

正常血清泌乳素(PRL)水平小于1.14nmol/L(或者小于等于30ng/mL),如果连续两次PRL含量高于正常值则诊断为高泌乳素血症。该疾病由多种原因引起、以血清泌乳素升高及其相关临床表现为主、下丘脑-垂体轴生殖内分泌紊乱综合征,是临床上常见、累及生殖以及内分泌和神经系统的一类疾患的统称。 病因及发病机制1)下丘脑疾病:颅咽管瘤、炎症等病变影响催乳素抑制因子的分泌,导致催乳素升高。2)垂体疾病:是引起高催乳素血症最常见的原因,以垂体催乳素瘤最常见。1/3以上患者为垂体微腺瘤(直

Olanzapine-Induced Hyperprolactinemia: Two Case Reports复制标题

奥氮平致高泌乳素血症2例报告

发表时间:2019-07-29

影响因子:3.8

作者: Pedro Cabral Barata

期刊: Frontiers in pharmacology

Hyperprolactinemia is a common consequence of treatment with antipsychotics. It is usually defined by a sustained prolactin level above the laboratory upper level of normal in conditions other than that where physiologic hyperprolactinemia is expected. Normal prolactin levels vary significantly among different laboratories and studies. Several studies indicate that olanzapine does not significantly affect serum prolactin levels in the long term, although this statement has been challenged.Our aim is to report two olanzapine-induced hyperprolactinemia cases observed in psychiatric consultations.

译文

高泌乳素血症是抗精神病药物治疗的常见后果。通常定义为持续的催乳素水平高于实验室正常水平,而不是生理性高催乳素血症。正常催乳素水平在不同的实验室和研究中有显著差异。一些研究表明奥氮平对血清催乳素水平的长期影响不明显,尽管这一说法受到质疑,我们的目的是报告两例奥氮平引起的高催乳素血症的精神科会诊。