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Single umbilical artery: what does it mean for the fetus? A case-control analysis of pathologically ascertained cases.
单脐动脉: 它对胎儿意味着什么?病理确诊病例的病例对照分析。

摘要

PURPOSE:To ascertain the frequency of chromosomal and other anomalies in fetuses with single umbilical artery.
METHODS:Placentas with single umbilical artery were identified from hospital pathology laboratory records. For each identified case, the next consecutive placenta with two umbilical arteries served as a control. Pathology records, maternal histories, and prenatal ultrasounds when available were reviewed for congenital anomalies, pregnancy complications, and maternal characteristics. When indicated, placental specimens, amniocytes, or neonatal bloods were karyotyped.
RESULTS:Single umbilical artery existed in 2.0% (97/4846) of pathological specimens. Fetuses with single umbilical artery had significantly more chromosomal (10.3% vs. 1.0%) and other congenital anomalies (27% vs. 8%).
CONCLUSIONS:The high incidence of major chromosomal and congenital anomalies justifies detailed fetal ultrasonography, echocardiography, and amniocentesis for karyotype when single umbilical artery is discovered during routine ultrasound.

译文

目的: 确定单脐动脉胎儿染色体及其他异常的频率。
方法: 从医院病理实验室记录中确定单脐动脉胎盘。对于每一个已确认的病例,下一个有两条脐动脉的连续胎盘作为对照。对病理记录、母体病史和产前超声波检查时的先天性异常、妊娠并发症和母体特征进行了审查。当需要时,胎盘标本、羊水细胞或新生儿血液进行染色体组。
结果: 2.0% (97/4846) 的病理标本中存在单脐动脉。单脐动脉的胎儿有明显更多的染色体 (10.3% 对 1.0%) 和其他先天性异常 (27% 对 8%)。
结论: 当在常规超声中发现单脐动脉时,主要染色体和先天性异常的高发生率证明了详细的胎儿超声检查、超声心动图和羊膜穿刺术的染色体组型。

single umbilical artery

妇产 产前诊断 疾病
概述  :  

 单脐动脉(single umbilical artery,SUA)是指胎儿先天性缺乏一条脐动脉,是脐带异常中最常见的一种,其中左侧缺失约占70%,右侧缺失约占30%。发生原因可能有以下3种:(1)已经出现的脐动脉中的一条发育不全;(2)先前正常的脐动脉萎缩或闭锁;(3)尿囊总动脉或脐总动脉的持续存在。 类型 单纯性:是指仅存在单脐动脉,胎儿未发现其它结构的异常,按期产检,一般来说胎儿预后好。 多发畸形:如果彩超提示胎儿有畸形,很少是单一的,几乎均是多

single ['sɪŋg(ə)l]  ['sɪŋgl]

       adj. 单一的;单身的;单程的  n. 一个;单打;单程票

       Yes, every single one of them. 当然,他们中的任何一个。

 

umbilical [ʌm'bɪlɪk(ə)l; ,ʌmbɪ'laɪk(ə)l]  [ʌm'bɪlɪkl]

       adj. 脐带的;母系的;中央的

       Objective: To diagnose the causes of umbilical exudation in infant. 目的:用超声诊断引起婴儿脐部渗液的病因。

 

artery ['ɑ:tərɪ]  ['ɑrtəri]

       n. 动脉;干道;主流

同根词   词根: artery

adj.arterial [解剖] 动脉的;干线的;像动脉的 

arteriolar 小动脉的

       In fact, about 25% of all strokes are caused by carotid artery disease. 实际上,大约有25%的脑卒中患者是由于颈动脉疾病引起的。

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