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首页 > 医学词汇大全 > infertility
infertility

妇产

关键词妇产 疾病 不孕不育

词汇介绍

拓展阅读

解析

infertility  英 [ˌɪnfɜːˈtɪləti] 美 [ˌɪnfɜːrˈtɪləti]

释    义   n. 不孕症;不肥沃,贫瘠

同根词   infertile   adj. infertile 不肥沃的;不毛的;不结果实的;不能生殖的

例    句   Some infertility experts worry about their health and development.  一些不孕不育专家为他们的健康和发育担忧。

概述

不孕(育)症是一组由多种病因导致的生育障碍状态,是育龄夫妇的生殖健康不良事件。如今随着辅助生殖技术的迅猛发展,已经帮助许多不孕夫妇获得后代,但也引起了一些伦理或法律问题,需要严格管理和规范。对于大多数女性患者而言,盆腔因素和排卵障碍是其不孕的主要病因,但多种病因可同时存在。故诊断时需男、女双方同时就诊,根据病史、排卵功能、输卵管通畅性和男方精液检查明确病因。女性无避孕性生活至少12个月而未孕即称为不孕症,对男性则称为不育症。不孕症分为原发性和继发性两大类,既往从未有过妊娠史,未避孕而从未妊娠

Unexplained infertility复制标题

不明原因不孕

发表时间:2018-10-27

影响因子:59.1

作者: Norbert Gleicher

期刊:Lancet

The study claimed to confirm the effectiveness of IUI in treating unexplained infertility. However, unexplained infertility is a historical non-diagnosis. As knowledge of the causes of infertility improved the term should have been either adjusted or, as we suggested in 2006, been abandoned. With more in-depth investigations, practically all couples with infertility can reach one or more real diagnoses. Instead, the authors defined patients as having unexplained infertility (ie, inability to conceive within 1 year) under the minimal criteria of being ovulatory, having bilaterally open fallopian tubes, and normal semen analyses. They did not have to be spontaneously ovulatory but could be ovulatory following medical ovulation induction, in itself an oxymoron as medical ovulation induction is treatment. Moreover, patient selection criteria in this study did not consider ovarian reserve parameters. Theoretically, a woman could have abnormally high folliclestimulating hormone amounts, or low anti-Müllerian hormone amounts, or both, and could still be ovulatory after treatments. However, her infertility would still be considered as unexplained if pharmacological ovulation induction had made her ovulatory, yet did not lead to pregnancy.

译文

这项研究声称证实了IUI治疗不明原因不孕症的有效性。然而,不明原因不孕症是一个历史性的非诊断。随着人们对不孕原因的认识不断提高,这一术语本应加以调整,或如我们在2006年所建议的那样,被抛弃。随着调查的深入,几乎所有不孕夫妇都能得到一个或多个真正的诊断。相反,作者将患者定义为在排卵、双侧输卵管开放和精液分析正常的最低标准下有不明原因的不孕(即1年内不能怀孕)。它们不必是自然排卵,但可以在药物诱导排卵后排卵,本身就是一个矛盾修饰语,因为药物诱导排卵是治疗。此外,本研究中的患者选择标准没有考虑卵巢储备参数。理论上,女性可能有异常高的促卵泡激素水平,或低的抗苗勒激素水平,或两者兼而有之,并且在治疗后仍可能排卵。然而,如果药物促排卵使她排卵,但没有导致怀孕,那么她的不孕仍然被认为是无法解释的。