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menopause

妇产

关键词妇产 临床研究术语 妇女生命自然进程

词汇介绍

拓展阅读

解析

menopause  英 [ˈmenəpɔːz]    美 [ˈmenəpɔːz]

释    义   n.绝经期;(妇女的)更年期          

同根词   menopausal   adj. 绝经期的,更年期的  

例    句   I'm going through menopause.  我大概到更年期了。

概述

绝经(menopause)指妇女一生中的最后一次月经,只能回顾性地确定。绝经是妇女生命自然进程中的一个生理现象。绝经年龄受遗传、地理、营养、生活习惯、嗜烟酒与健康史等因素的影响。世界范围内自然绝经的年龄为45-55岁,平均为48-51岁。发达国家的绝经年龄中位数为50-52岁,发展中国家及亚非拉地区中位数为47岁左右。 分类及生理变化月经是每个正常女性都会有的一种情况,因为有了正常的月经出现,女性身体内部的激素才会正常,但是当女性们随着年龄的增长,月经的情况就可能会逐渐的发生改变,

The association of birthweight with age at natural menopause: a population study of women in Norway复制标题

自然绝经时出生体重与年龄的关系: 挪威妇女的人口研究

发表时间:2019-10-21

影响因子:7.3

作者: Elisabeth K Bjelland

期刊:Int J Epidemiol

Menopause is the final marker of the end of a woman’s reproductive period. Natural menopause occurs between the age of 40 and 60 years in most women. Early menopause (<45years old) is associated with increased risk of cardiovascular disease and all-cause mortality, and late menopause (55years old) increases the risk of certain hormone-related cancers after menopause. Although genetic factors play a role, the mechanisms underlying the timing of menopause are not well understood. Previous studies suggest that factors in very early life may influence age at menopause. A woman is born with a certain number of ovarian follicles, and menopause occurs when the number of ovarian follicles has decreased to a critically low level. It is assumed that no new ovarian follicles are developed after the 20th week of fetal life, and that atresia of the ovarian follicles follows thereafter. Thus, the initial number of ovarian follicles and the speed of follicle atresia during fetal life, may be important for a woman’s number of ovarian follicles at birth, and thereby the timing of her menopause.

译文

更年期是女性生殖期结束的最后标志。自然更年期发生在40至60岁之间的大多数妇女。早期绝经(<45岁)与心血管疾病和全因死亡率增加相关,晚期绝经(55岁)增加绝经后某些激素相关癌症的风险虽然遗传因素起作用,但绝经时间的机制还不清楚先前的研究表明,生命早期的因素可能会影响更年期的年龄。女性出生时有一定数量的卵泡,当卵泡数量减少到极低水平时,就会发生更年期。假设胎儿出生后20周没有新的卵泡发育,此后卵泡闭锁。因此,胎儿期卵泡的初始数量和卵泡闭锁的速度,可能对一个妇女出生时的卵泡数量,进而对其更年期的时间很重要。