内分泌
词汇介绍
拓展阅读
解析
Thyroid 英 /ˈθaɪrɔɪd/ 美 /ˈθaɪrɔɪd/
释 义 n. 甲状腺;甲状软骨;甲状腺剂
adj. 甲状腺的;盾状的
例 句 I believe that thyroid hormone treatment should not be given to all overweight subjects. 我相信甲状腺激素治疗并不适用于所有的肥胖病人。
Storm 英 /stɔːm/ 美 /stɔːrm/
释 义 n. 暴风雨;大动荡
vi. 起风暴;横冲直撞;狂怒咆哮
vt. 猛攻;怒骂
n. (Storm)人名;(瑞典)斯托姆;(德)施托姆;(英、西、芬)斯托姆
同根词 stormy adj. 暴风雨的;猛烈的;暴躁的
storminess n. 风暴度;磁暴度;猛烈
例 句 It could, however, be the calm before the storm. 然而,那可能是暴风雨前的平静。
概述
The Delayed Diagnosis of Thyroid Storm in Patients with Psychosis: A Report of Two Cases复制标题
精神病患者甲状腺风暴的延迟诊断 (附2例报告)
发表时间:2019-08-01
影响因子:1.0
作者: Yuki Ishihara
期刊:Intern Med
In the first case, the patient recognized worsening of her depression, a decreased food intake, and extensive fatigue. However, she adopted the “wait and see” approach, presuming her CNS symptoms associated with thyroid storm to be psychiatric in origin. In the second case, the patient had a history of palpitation and chest tightness. However, he initially discounted the symptoms and not informed his doctor. Thyroid storm is a lethal disease that requires early detection and treatment. If these patients had undergone thyroid hormone measurements when their mental or physical statuses had changed, we might have been able to detect and treat their thyroid conditions earlier. CNS manifestations of thyroid storm may include restlessness, delirium, mental aberration, somnolence, convulsions, and coma. However, depression, hypomania, and anxiety disorders are the most frequently reported psychiatric findings in patients with hyperthyroidism. The mechanisms for underlying these are thought to involve sympathetic nerve activation, increased β-adrenergic activity, and the autoimmune process. In addition, thyroid hormones are thought to have a modulating effect on the serotonin system in the brain and induce direct effects on cerebral tissue, which cause electroencephalogram abnormalities. However, why CNS manifestations appear during a thyroid storm are unclear. In Japan, CNS manifestations were been reported in 67.4% of patients with thyroid storm and 84.4% of patients with a definite diagnosis. More than half of patients with a definite diagnosis had an abnormal GCS (53.5%) and/or Japan Coma Scale score (62.6%). A lower GCS has been significantly associated with the development of irreversible deficits, making it essential that we correctly identify CNS manifestations in patients with a thyroid storm.
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