释 义 n. 星状胶质细胞
例 句 Astroglial cells or astrocytes are specialized cells that support neuron function with nutrients and protective buffering.星形胶质细胞是一种特殊细胞，它能够通过释放营养素和缓冲保护作用支持神经元的功能。
作者： Rupali Sharma
Previous studies have shown that astrocytes have diverse functions such as establishing direct contact with neurons and secreting soluble factors at the pre-and post-synaptic sites thus modulating the structure and function of both excitatory and inhibitory synapses leading to changes in synaptic transmission. In regards to hypobaria-hypoxia, it has been shown that there is an increase in astrogliosis in the CA1 region of the hippocampus, as indicated by elevated expression of GFAP86,87. As further novelty, our findings reveal a decrease in GFAP expression in the cerebellum. It is intriguing that we observed these additional changes in the cerebellum, although at a different time point. A study by Dheer et al. studied CEHA in rats, where they observed activation of astrocytes in CA1 region of hippocampus at 7 and 14 days exposure; while Li et al., observed increased GFAP expression between 7–14 days in cortex and brainstem. The apparent discrepancy between our and their results could be due to multiple factors. One major factor is represented by the time duration, our mice in fact were exposed to a longer duration of HA, which is a chronic exposure, while their rats were exposed for a shorter period of time. Another difference is in the pressure of the hypobaric chamber, which was p=282mm/Hg (equivalent to 5.45psi) for their experiments, and ~7.4psi (equivalent to 382.69mm/Hg) for our experiments. A further difference consists in their experimental animals, which were rats while ours were mice. All these factors could have contributed to the apparent discrepancy and it is possible then that the observed decrease in GFAP, along with the decrease in other synaptic proteins, are indeed signals of decreased synaptic activity in a more generalized context of neuroplasticity occurring in response to CEHA.