Hirsutism 英 /'hɜːsjuːtɪz(ə)m/ 美 /'hɝsʊ,tɪzəm/
释 义 n. 多毛症（尤指妇女多毛症）
例 句 Most medications used to treat hirsutism are approved by the Food and Drug Administration, but not for this specific indication. 治疗多毛症的多数药物经食物和药物管理局批准，但不是以这专业为指征。
作者： Anna Fuchs
Hyperandrogenaemia is a very frequent endocrinopathy. It concerns about 7% of women in childbearing age. Its clinical symptoms can be pretty troublesome and often affect our patients’ self-esteem. Oral contraceptives, many times viewed only as a method of contraception, turn out to be very useful in those conditions and offer a variety of non-contraceptive health benefits. They are becoming more and more popular in women with higher levels of androgens. Additionally, they reduce menstrual pain and the amount of blood loss during the menstruation. Moreover, taking hormonal contraceptives regulates the menstrual cycle. Hyperandrogenaemia can be caused by different disease entities, for example polycystic ovary syndrome, obesity, Cushing syndrome, varian secreting androgens, adrenal tumors, adrenal hyperplasia, liver insufficiency. The most common symptoms connected with higher levels of androgens are hirsutism and acne. Hirsutism affects about 5–15% and acne about 6–55% of women, according to epidemiological data. Physiologically, androgens are responsible for hair growth regulation, production and secretion of gonadotropins, wound healing and cutaneous barrier formation. The pathogenesis of acne and hirsutism in hyperandrogenaemia is connected with sebaceous glands, hair follicles and enzymatic reactions in them. Androgens are converted into the dihydrotestosterone (DHT) which has 5 to 10 times higher affinity to androgen receptor than testosterone.