摘要

Dizziness is a common complaint in primary care clinics and can enter the diagnostic profile of different pathologies spanning from psychiatric problems to vestibular dysfunction. Episodes of vertigo in Ménière's patients are often reported to be triggered by stress but no physiological data are available to account for the subjective link. The study involved 42 Ménière's patients hospitalized for neurectomy of the vestibular nerve for relief of incapacitating vertigo. In addition 18 patients with neurinoma of the vestibular nerve and 12 patients with facial spasm, who underwent surgery, served as controls. A blood sample was taken on the day of surgery in order to determine the level of battery of different stress hormones. The most striking observation was the presence of hyperprolactinemia (above 20 microg/l) in 14 Ménière's patients. The presence of prolactinoma was confirmed by MRI in six cases out of six investigated and the others have not yet been followed up in this retrospective study. These observations are clearly indicative for systematic determination of prolactin levels before opting for surgery in Ménière's patients.

译文

头晕在初级保健诊所是一种常见的疾病,可以进入从精神疾病到前庭功能障碍的不同病理的诊断模式。据报道,梅尼埃患者的眩晕发作通常是由压力引发的,但没有生理数据可以解释主观联系。这项研究涉及 42 名因前庭神经神经切除术而住院的梅尼埃患者,以缓解丧失能力的眩晕。此外,18 名前庭神经神经瘤患者和 12 名面肌痉挛患者接受了手术,作为对照组。手术当天采集了血样,以确定不同应激激素的水平。最引人注目的观察是 14 名梅尼埃患者存在高催乳素血症 (超过 20 微克/升)。在这项回顾性研究中,六个调查病例中有六个病例的催乳素瘤的存在被 MRI 证实,其他病例尚未得到随访。这些观察清楚地表明,在梅尼埃患者选择手术之前,系统测定催乳素水平。

Prolactinoma

内分泌 催乳素分泌过度 疾病
概述  :  

催乳素瘤是大脑脑垂体的非癌性肿瘤(腺瘤)过度分泌激素催乳素的疾病。主要作用是降低某些性激素的水平,即女性的雌激素和男性的睾丸激素。尽管泌乳素瘤不会危及生命,但会损害视力,引起不育并产生其他影响。催乳素瘤是最常见的激素分泌型肿瘤,可在垂体中发展。医生通常可以用药物治疗催乳素,使催乳素水平恢复正常,手术切除垂体瘤也是一种选择。临床表现绝经前妇女的催乳素瘤症状:①催乳素的少量增加会导致月经不调或月经完全消失,由于这种明显的症状,绝经前妇女的泌乳素瘤通常在肿瘤较小的情况下早期诊断出来;②乳房产生乳汁

Prolactinoma   英/prəu'læktinəmə/

释    义   n. 泌乳素瘤

例    句   Objective To investigate the clinical characteristics, therapies and prognosis of male adolescent patients with prolactinoma. 目的探讨男性青少年催乳素瘤的临床特点、治疗与预后。

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