消化
词汇介绍
拓展阅读
解析
fical 英 [ˈfiːkl] 美 [ˈfiːkl]
释义 adj. 排泄物的;残渣的;糟粕的
例句 Fecal matter should move through your colon easily and in a short time. 粪便的问题应该通过您的结肠容易在很短的时间。
immunochemical 英 [,ɪmjʊnəʊ'kemɪkəl]
释义 adj. 免疫化学的
例句 Within the last year, have you had a fecal occult blood test (FOBT) or a fecal immunochemical test (FIT)? 过去一年内,是否曾接受过大便隐血测试或大便免疫化学测试?
test 英 [test]
释义 n. 测验,考查;测试;检验;化验
v. 测验;化验,检查;试验,测试;考验
例句 You should test for the overload at each point of the cycle. 您应当在周期的每个时刻都测试超负荷。
概述
较低的异常粪便免疫化学检测临界值可提高系统水平筛查中的结直肠癌检测
发表时间:2019-05-11
影响因子:8.0
作者: Emily Berry
期刊:Clinical Gastroenterology and Hepatology
Colorectal cancer (CRC) is the second leading cause Q16 of cancer death in the United States (ACS-CFF). Q15 Screening can reduce CRC incidence and mortality,1–6 but participation is suboptimal among underserved populations, particularly minorities and the uninsured.2,7–10 Noninvasive tests for CRC screening such as the fecal immunochemical test (FIT) have been linked to higher participation rates,6,11–13 but have lower sensitivity for CRC and advanced adenoma than colonoscopy. Some FITs are quantitative and measure the absolute hemoglobin (Hgb) concentration within a stool sample. One strategy to improve neoplasia detection among individuals preferring FIT would be to decrease the Hgb concentration that would indicate an abnormal test result requiring diagnostic colonoscopy. Prior work has suggested that a lower threshold can improve neoplasia detection; a meta-analysis of FIT performance found that using a lower hemoglobin concentration cut-off value to designate an abnormal FIT optimized sensitivity for CRC: 89% for a cut-off value of less than 20 mg hemoglobin/g feces vs 70% for cut-off values of 20 to 50 mg hemoglobin/g feces.14 A challenge of this approach, however, particularly in settings with constrained colonoscopy capacity, is that decreasing the threshold also may increase colonoscopy demand. In the United States in particular, real-world data specific to the impact of using a lower Hgb concentration threshold for diagnostic colonoscopy demand and neoplasia detection when implemented within screening programs are sparse.
译文