esophageal 英 [iː,sɒfə'dʒiːəl] 美 [,isə'fædʒɪəl]
释义 adj. 食管的；食道的
例句 Research and application of tumor markers in esophageal squamous cell carcinoma. 肿瘤标志物在食管鳞状细胞癌中的研究与应用。
释义 n. 闭锁（畸形）；无孔；不通（如子宫，输卵管）
例句 Objective: To discuss the feasibility and operation sequence for congenital atresia of esophagus by stomach pipe. 目的：探讨应用胃管初步诊断先天性食管闭锁的可行性及操作程序。
作者： Berengere Franc¸ois
期刊：The Journal of Pediatrics
Esophageal atresia is a rare congenital malformation characterized by a lack of continuity of the upper gastrointestinal tract with or without a tracheoesophageal fistula. Esophageal atresia occurs in 1 in 2400-4500 births.1 The prognosis for esophageal atresia has benefited from recent advances in medical and surgical care; the survival rate is now >95%, and an increasing number of patients live to adulthood.2–5 Gastroesophageal reflux disease (GERD) is the most frequent associated condition and occurs in the majority of patients with esophageal atresia.6 The cause of GERD in esophageal atresia involves abnormal extrinsic and intrinsic innervation of the esophagus, which leads to dysmotility and anomalies in sphincter tone.6–8 GERD can have potentially severe complications, such as peptic esophagitis, gastric metaplasia, Barrett esophagus, anastomotic stricture, aggravation of laryngomalacia, and asthma. GERD associated with esophageal atresia often is refractory to antireflux medication, and up to 40% of patients may require antireflux surgery.