释义 adj. 腹会阴的
例句 Among locally advanced rectal/rectosigmoid cases, surgery included abdominoperineal resection or low anterior resection.
resection 英 [rɪ'sekʃn] 美 [rɪ'sekʃn]
释义 n. [外科] 切除术
例句 Local residual early cancer after endoscopic resection
作者： Milan Spasojevic
期刊：Ann Surg Oncol
Treatment of low locally advanced rectal cancer (LARC) frequently requires abdominoperineal resection (APR), often in combination with multivisceral resections,1 resulting in a large dead space in the pelvic cavity and the risk of non-tension-free closure of the perineal wound. In addition, the majority of the patients receive neoadjuvant (chemo) radiotherapy (C)RT, which, in combination with the above-mentioned factors, predisposes patients to surgical site infection and delayed perineal wound healing.2–4 These complications contribute to prolonged hospital stay and the necessity for repeat wound debridement, adversely affecting the patients’ quality of life and significantly increasing the cost of medical treatment.5 In an attempt to reduce perineal wound morbidity, the vertical rectus abdominis musculocutaneous (VRAM) flap repair has been advocated as a valuable alternative to direct perineal wound closure, with a reported absolute risk reduction of perineal wound complications of up to 17%.6 The rationale behind this is that the placement of nonirradiated, well-vascularized tissue to the perineal wound improves wound healing. However, due to the heterogeneity of present studies7–10 and the absence of sufficiently powered prospective studies,11 the efficacy of VRAM flap in reducing perineal wound morbidity remains uncertain. The aim of this study was to compare perineal wound morbidity after APR for LARC in patients with VRAM flap repair to direct perineal wound closure.