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Hemolytic Jaundice

消化

关键词消化 疾病 胆红素

词汇介绍

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解析

hemolytic [hi:'mɒlɪtɪk]  [hi:'mɒlɪtɪk]

释义   adj. [生理][免疫] 溶血的

例句   Objective:To compare the prediction effect on hemolytic disease of the newborn between monocyte monolayer assay and antibody titre.

目的单核细胞单层试验和抗体效价测定试验预判新生儿溶血病的预测效果。

 

jaundice  [ˈdʒɔ:ndɪs]  [ˈdʒɔndɪs, ˈdʒɑn-]

释义   n. 黄疸;偏见;乖僻

vt. 使怀偏见;使患黄疸

例句   Leptospirosis causes severe jaundice, kidney failure and bleeding in the lungs.

钩端螺旋体导致严重的黄疸、肾衰竭和肺出血。


概述

血清总胆红素在34 umol/L以上,临床上即表现有黄疸。巩膜、皮肤无黄染,而血清总胆红素超过正常值,则称为隐性黄疸。溶血性黄疸(hemolytic jaundice)指由于各种原因造成的红细胞被大量破坏,在网状内皮细胞中生成的胆红素过多,超过肝摄取、结合与排泄的能力,造成血中间接胆红素浓度异常增高引起的黄疸。各种引起大量溶血的原因都可造成溶血性黄疸。 病因凡能引起溶血的疾病都可引发溶血性黄疸。常见病因如下:(1)先天性溶血性贫血 如海洋性贫血、遗传性球形红细胞增多症等;

31-Year-Old Woman With Jaundice and Abdominal Pain复制标题

31岁妇女,黄疸和腹痛

发表时间:2019-09-01

影响因子:7.1

作者: Daniel D. Penrice

期刊:Mayo Clin. Proc.

A31-year-old woman presented with a 3-month history of persistent jaundice. She worked as a school teacher and a student had made a comment that her eyes appeared yellow approximately 3 months before presentation. During this time, she had also noticed darkening of her skin diffusely. She had believed that these changes were secondary to indoor tanning, which she did once weekly. One week prior she developed sharp right upper quadrant abdominal pain that was worse with lying on her right side. She also began to appreciate mild lower extremity edema and darkening of  her urine. Her medical history was notable for alcohol use disorder, obesity status post Roux-en-Y gastric bypass with current body mass index of 31 kg/m2 , seizure disorder, and major depressive disorder. She first began consuming alcohol at age 16 and had prolonged periods of alcohol abuse with intermittent episodes of sobriety. One year prior, she had undergone an intensive inpatient alcohol rehabilitation program. However, she admitted consuming alcohol following completion of rehabilitation, approximately “once per week.” Her last drink was three days before presentation. She was taking no medications at the time of her presentation.

译文

A31岁的女性患有持续性黄疸3个月的病史。她是一名学校老师,一名学生发表评论称她的眼睛在出现前约3个月出现黄色。在此期间,她也注意到她的皮肤弥漫性变暗。她相信这些变化是室内鞣制的次要因素,她每周做一次。一周前,她出现了严重的右上腹部疼痛,右侧卧位疼痛更严重。她也开始意识到轻度的下肢水肿和尿液变黑。她的病史以酒精使用障碍,Roux-en-Y胃旁路术后的肥胖状态,当前体重指数为31 kg / m2,癫痫发作和重度抑郁症而着称。她16岁时开始饮酒,长期酗酒,间歇性清醒。一年前,她接受了强化住院酒精康复计划。然而,她承认在康复完成后饮酒,大约“每周一次。”她的最后一次饮酒是在出现前三天。她在演讲时没有服用任何药物。