short 英 [ʃɔ:t] 美 [ʃɔ:rt]
释义 adj. 短的；不足的；矮的，低的
例句 Short-term successful outcomes have been described.
bowel 英 [ˈbaʊəl] 美 [ˈbaʊəl, baʊl]
释义 n. 肠；内部；同情
例句 Bowel dilatation was diagnosed when small bowel diameter exceeded 7 mm or large bowel diameter exceeded 18 mm.
肠扩张的诊断根据小肠直径超过7 mm或者大肠直径超过18 mm。
syndrome 英 [ˈsɪndrəʊm] 美 [ˈsɪndroʊm]
释义 n. [临床] 综合症状；并发症状；校验子；并发位
例句 Anterior capsular phimosis syndrome.
作者： Douglas L. Seidner
期刊：J Parenter Enteral Nutr
The clinical features of intestinal failure associated with short bowel syndrome (SBS-IF), including parenteral support (PS; parenteral nutrition, and/or intravenous fluids) volume needs, vary according to the extent and cause of intestinal resection and residual anatomy.1-3 Teduglutide, a glucagon-like peptide (GLP)-2 analogue, is approved in the United States and Europe for the treatment of patients aged 1 year with SBS-IF,4,5 and has been shown to improve intestinal absorption and reduce PS requirements in patients with SBS-IF.6-8 In the phase III, 24-week, placebo controlled STEPS study (NCT00798967; EudraCT, 2008- 006193-15), individual patient response to teduglutide in terms of PS volume reduction was variable, with PS volume change from baseline at week 24 ranging from –1993 to 329 mL/d.2 Recently, Jeppesen et al evaluated clinical and disease characteristics associated with PS volume reduction with teduglutide treatment in patients from the STEPS study.2 Among all patients treated with teduglutide, absolute baseline PS volume requirements were significantly correlated with absolute PS volume reduction; no correlation was seen among placebo-treated patients. Compared with other remnant bowel anatomies, patients with a jejunostomy or ileostomy and no colon remaining had the highest PS volumes at baseline and experienced the greatest PS volume reductions with teduglutide. Compared with vascular or other causes of SBS-IF, patients with inflammatory bowel disease (IBD) as a cause of SBS-IF had higher PS volume requirements at baseline and experienced the greatest PS volume reductions with teduglutide.