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首页 > 医学词汇大全 > Gastric Adenocarcinoma
Gastric Adenocarcinoma

消化

关键词消化 临床研究术语 胃黏膜上皮肿瘤

词汇介绍

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解析

gastric 英 [ˈgæstrɪk] 美 [ˈɡæstrɪk]

释义   adj. 胃的;胃部的

例句   But if you think gastric bypass surgery might be right for you, talk with your doctor.

但是如果你认为胃分流术适合你,你可以与你的医生讨论一下。

 

adenocarcinoma 英 [ˌædnəʊˌkɑ:sə'nəʊmə] 美 [ˌædnoʊˌkɑ:sə'noʊmə]

释义   n. [肿瘤] 腺癌;恶性腺瘤

复数 adenocarcinomas或 adenocarcinomata

例句   This kind of adenocarcinoma is usually undifferentiated with early metastasis through lymph gland .

这种腺癌通常在通过淋巴结转移的早期是未分化的。

概述

 胃癌( gastric cancer)或胃腺癌( gastric adenocarcinoma)是指发生于胃黏膜上皮的恶性肿瘤,约占所有胃恶性肿瘤的95%以上。 病因和发病机制 (1)病因确切病因尚未完全阐明,但病因属多因素,是幽门螺杆菌( Helicobacter pylori,简称H. pylori)感染、环境因素和遗传因素协同作用的结果已成为共识。少部分胃癌,特别是病理组织学上显示未分化型的胃癌,其发生可能与EB病毒感染相关。 (2)胃癌的癌前

Total gastrectomy in patients with gastric adenocarcinoma: Is there an advantage to the minimally invasive approach?复制标题

胃腺癌患者的全胃切除术: 微创方法有优势吗?

发表时间:2019-07-17

影响因子:3.6

作者: Patrick J

期刊:Surgery

Consensus treatment recommendations for resectable gastric tumors involves total or partial gastric resection to achieve negative margins and en bloc resection of ≥15 D1 and D2 lymph nodes.1-3 Patients with advanced disease or proximal tumors often require a total gastrectomy (TG) with Roux-en-Y reconstruction. These operations are associated with significant postoperative morbidity.4,5 Many have advocated for the application of minimally invasive (MIS) techniques to these procedures in an effort to reduce postoperative morbidity. Most comparisons of MIS and open approaches to gastrectomy are retrospective reviews of single institutional experiences with subtotal gastrectomy or distal gastrectomy evaluating small numbers of patients during time periods before implementation of robotic approaches. These studies have all varied considerably in their reporting of oncological outcomes including node counts, tumor staging, and resection margin status. Very few evaluate postoperative outcomes for TG and evaluate outcomes for longer than 30 days after the index procedure.6-9 The limitations on sample size and reporting of perioperative oncologic outcomes and the fact that robotic procedures are not included make it difficult to definitively  assess the efficacy of the MIS approach. In the present work, we utilize the National Cancer Database (NCDB) to evaluate the independent effect of the MIS approach to TG on short-term perioperative oncologic and clinical outcomes and long-term overall survival (OS) in patients undergoing MIS or open TG for gastric adenocarcinoma between 2010 and 2015.

译文

针对可切除的胃肿瘤的共识治疗建议涉及全部或部分胃切除以获得≥15D1和D2淋巴结的阴性切缘和整块切除.1-3晚期疾病或近端肿瘤患者通常需要与Roux进行全胃切除术(TG) -en-Y重建。这些手术与术后发病率显着相关[4,5]。许多人主张将微创(MIS)技术应用于这些手术,以减少术后发病率。 MIS和胃切除术的开放式方法的大多数比较是回顾性评估单个机构经验,即在实施机器人方法之前的时间段期间进行胃大部切除术或远端胃切除术评估少数患者。这些研究在报告肿瘤学结果方面有很大差异,包括淋巴结计数,肿瘤分期和切除边缘状态。很少有人评估TG的术后结果,并在指数手术后超过30天评估结果.6-9样本量的限制和围手术期肿瘤学结果的报告以及不包括机器人手术的事实使得很难明确评估MIS方法的功效。在目前的工作中,我们利用国家癌症数据库(NCDB)来评估MIS方法对TG的短期围手术期肿瘤和临床结果以及接受MIS或开放TG的患者的长期总生存期(OS)的独立影响。适用于2010年至2015年间的胃腺癌。