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首页 > 医学词汇大全 > Hepatic Encephalopathy
Hepatic Encephalopathy

消化

关键词消化 疾病 临床疾病

词汇介绍

拓展阅读

解析

hepatic  [hɪˈpætɪk] [hɪˈpætɪk]

释    义   adj. 肝的;肝脏色的;治肝病的

同根词   hepatitis n. 肝炎

例    句   Hepatic encephalopathy is a chronically debilitating complication of hepatic cirrhosis.

肝性脑病是肝硬化长期衰弱的并发症。

 

encephalopathy  [enˌsefəˈlɒpəθi] [enˌsefəˈlɑ:pəθi]

释    义   n. []脑病

同根词   encephalopathia n. 脑病

adj.encephalopathic  脑病的

例    句   However, therapeutic strategies forneonatal encephalopathy remain scarce.

但是新生儿脑病的治疗措施缺非常稀少。

概述

肝性脑病(hepatic encephalopathy,HE),是肝功能衰竭或门体分流引起的中枢神经系统神经精神综合征,主要临床表现可以从人格改变、行为异常、扑翼样震颤( flapping tremor,asterixis)到出现意识障碍、昏迷。最常见于终末期肝硬化。如果肝脏功能衰竭和门体分流得以纠正,则肝性脑病可以逆转,否则易于反复发作。 病因1、肝脏病史:病毒、酒精、药物、毒物等引起肝细胞变形坏死,引起肝细胞代谢障碍。2、发病机制:肝性脑病的发病机制迄今为止仍不清楚。目前认为H

How to diagnose and manage hepatic encephalopathy: a consensus statement on roles and responsibilities beyond the liver specialist复制标题

如何诊断和管理肝性脑病: 肝脏专家之外的角色和责任的共识声明

发表时间:2016-02-15

影响因子:2.2

作者: Shawcross DL

期刊:EUR J GASTROEN HEPAT

In developing these statements we have acknowledged that making a definitive diagnosis of HE can be difficult. However, it is possible for all those healthcare providers who encounter patients with cirrhosis to identify cognitive impairment and be aware of HE in terms of the impact on patients. For those healthcare providers who do not have primary responsibility for management of patients with cirrhosis we believe that it is reasonable that patients with suspected HE are referred to their  gastroenterologist or liver specialist. It is then the responsibility of the primary provider (gastroenterologist or liver specialist) to ensure that appropriate clinical assessments are undertaken to make a diagnosis of overt HE. The use of psychometric and neurophysiological tests is essential to identify minimal HE, but the authors also felt they can be useful in the assessment of lower  grades of overt HE. Gastroenterologists who have appropriate training and facilities/equipment should be prepared to supplement clinical assessment with such tests. If appropriate facilities or trained staff are not available, discussion with a liver specialist or liver unit should be considered. As HE is a decompensation event, such a discussion can be helpful to allow prompt consideration  of whether the patient should be evaluated for liver transplantation.

译文

在开发这些陈述时,我们承认对HE进行明确诊断可能很困难。然而,所有那些遇到肝硬化患者的医疗服务提供者都有可能识别认知障碍并且在对患者的影响方面意识到HE。对于那些对肝硬化患者的管理没有主要责任的医疗保健提供者,我们认为将疑似HE患者转诊给他们的胃肠病学家或肝脏专家是合理的。然后,主要提供者(胃肠病学家或肝脏专科医生)有责任确保进行适当的临床评估以诊断明显的HE。心理测量和神经生理学测试的使用对于确定最小的HE是必不可少的,但作者也认为它们可用于评估较低等级的明显HE。应该准备具有适当培训和设施/设备的胃肠病学家,以通过这些测试补充临床评估。如果没有适当的设施或训练有素的工作人员,应考虑与肝脏专科医生或肝脏单位进行讨论。由于HE是失代偿事件,这样的讨论可以有助于及时考虑是否应该评估患者的肝移植。(摘自Shawcross DL1,Dunk AA,Jalan R,Kircheis G,de Knegt RJ,Laleman W,Ramage JK,Wedemeyer H,Morgan IE;新见解指导委员会。如何诊断和治疗肝性脑病:关于肝脏专家以外的角色和责任的共识声明。)