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首页 > 医学词汇大全 > Carcinoma of Pancreas
Carcinoma of Pancreas

消化

关键词消化 疾病 临床疾病

词汇介绍

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解析

carcinoma  [ˌkɑ:sɪˈnəʊmə]  [ˌkɑ:rsɪˈnoʊmə]

释义   n. [肿瘤]

例句   This is another papillary carcinoma of thyroid.

这是甲状腺乳头状癌的又一实例。

 

pancreas  [ˈpæŋkriəs]  [ˈpæŋkriəs, ˈpæn-]

释义   n. [解剖] 胰腺

例句   Ectopic pancreas is a rare congenital anomaly.

异位胰腺是一种罕见的先天性异常。 

概述

胰腺癌(carcinoma of pancreas)是发生于胰腺外分泌腺的恶性肿瘤。胰腺恶性肿瘤可来自胰腺外分泌腺、内分泌腺或非上皮组织,其中95%为胰腺癌。近20年来胰腺癌发病率呈增加趋势,其恶性程度高、发现多为中晚期,预后极差。发病年龄以45~70岁居多,40岁以下患者小于2%,男女比约为1.3~1.8:1。 病因和发病机制胰腺癌的病因和发病机制不明。流行病学调査资料显示,发病危险因素有吸烟、高脂和高蛋白饮食、遗传、糖尿病、慢性胰腺炎、胆石症、嗜酒、饮咖啡、某些化学致

Imaging features of undifferentiated carcinoma of the pancreas复制标题

胰腺未分化癌的影像学特征

发表时间:2019-07-03

影响因子:1.2

作者: Ishigami K

期刊:J Med Imaging Radiat Oncol

Undifferentiated carcinoma of the pancreas (UCP) with osteoclast-like giant cells (OCGC), classifications proposed by the World Health Organization (WHO),1is equivalent to anaplastic carcinoma of the pancreas(ACP). ACP was first described by Sommere et al. in 1954.2 ACP is a rare subtype of pancreatic ductal adenocarcinoma,which comprises only 0.25% of all pancreatic  ductal adenocarcinoma cases.3 According to the Japan Pancreas Society, ACP is classified into three types: pleomorphic type, spindle-cell type and ACP with OCGC.4In this article, we prefer to use the WHO term ‘undifferentiated carcinoma of the pancreas (UCP)’ rather than ACP for consistency with the international literature.UCP imaging findings have been primarily described in individual case reports5,6in the field of diagnostic radiology.Only a few case series have been previously  published.7,8Although UCP was believed to be notorious for its poor prognosis, recent study has reported that UCP with OCGC was better prognosis than pancreatic adenocarcinoma without OCGC.9Therefore, the diagnosis of UCP may not discourage from performing surgical resection, and it is worthwhile clarifying the imaging features of UCP for patient management.The purpose of this retrospective study was to evaluate multidetector-row CT (MDCT) and magnetic resonance  imaging (MRI) features of UCP with and without OCGC.

译文

未分化的胰腺癌(UCP)与破骨细胞样巨细胞(OCGC),世界卫生组织(WHO)提出的分类,1相当于胰腺间变性癌(ACP)。 Sommere等人首次描述了ACP。在1954年,ACP是一种罕见的胰腺导管腺癌亚型,仅占所有胰腺导管腺癌病例的0.25%.3根据日本胰腺学会的说法,ACP分为三种类型:多形性,梭形细胞型和ACP与OCGC .4在本文中,我们倾向于使用WHO术语“未分化的胰腺癌(UCP)”而不是ACP来与国际文献保持一致.UCP成像结果主要描述于个体病例报告中.5在放射诊断领域虽然UCP被认为因其预后不良而臭名昭着,但最近的研究报道,UCP与OCGC相比,预后不如没有OCGC的胰腺癌。因此,UCP的诊断可能并非如此。不鼓励进行手术切除,值得澄清UCP对患者管理的影像学特征。本次回顾的目的研究是评估UCP的多排螺旋CT(MDCT)和磁共振成像(MRI)特征,有无OCGC。