摘要

Over the last several decades, radionuclide myocardial perfusion imaging (MPI) with single photon emission tomography and positron emission tomography has been a mainstay for the evaluation of patients with known or suspected coronary artery disease (CAD). More recently, technical advances in separate and complementary imaging modalities including coronary computed tomography angiography, computed tomography perfusion, cardiac magnetic resonance imaging, and contrast stress echocardiography have expanded the toolbox of diagnostic testing for cardiac patients. While the growth of available technologies has heralded an exciting era of multimodality cardiovascular imaging, coordinated and dispassionate utilization of these techniques is needed to implement the right test for the right patient at the right time, a promise of "precision medicine." In this article, we review the maturing role of MPI in the current era of multimodality cardiovascular imaging, particularly in the context of recent advances in myocardial blood flow quantitation, and as applied to the evaluation of patients with known or suspected CAD. 

译文

在过去的几十年里，放射性核素心肌灌注成像 (MPI) 单光子发射断层扫描和正电子发射断层扫描已经成为评估已知或疑似冠状动脉疾病 (CAD) 患者的支柱。最近，独立和互补的成像方式的技术进步，包括冠状动脉计算机断层扫描血管造影术、计算机断层扫描灌注、心脏磁共振成像, 对比压力超声心动图已经扩展了心脏患者诊断测试的工具箱。虽然现有技术的发展预示着一个多模态心血管成像的激动人心的时代，但需要协调和冷静地利用这些技术，以便在正确的时间为正确的患者实施正确的测试, “精准医疗” 的承诺。在这篇文章中，我们回顾了 MPI 在当前多模态心血管成像时代的成熟作用，特别是在心肌血流定量的最新进展的背景下, 并应用于已知或疑似 CAD 患者的评估。