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Reduced and delayed untwisting of the left ventricle in patients with hypertension and left ventricular hypertrophy: a study using two-dimensional speckle tracking imaging.
高血压和左心室肥厚患者左心室的减少和延迟解旋: 一项使用二维斑点追踪成像的研究。

摘要

AIMS:Newly developed two-dimensional ultrasound speckle tracking imaging allows measurements of left ventricular (LV) rotation and twist. Because LV untwisting predominantly occurs during the isovolumic relaxation period, its assessment reflects the process of LV relaxation. The aim of this study was to examine whether LV hypertrophy (LVH) adversely affects LV untwisting and abnormalities in LV untwisting could become a novel marker in assessing LV relaxation abnormalities.
METHODS AND RESULTS:We acquired basal and apical LV short-axis images in 49 hypertensive patients. Using two-dimensional strain software, a time-domain speckle tracking was performed, and the mean value of LV rotation was obtained at each plane. LV twist was defined as apical rotation relative to the base. In order to adjust for inter-subject differences in heart rate, the time sequence was normalized to the percentage of systolic and diastolic duration. The degree of LV untwisting was calculated as the percentage of systolic twist : untwisting = (TwistES-Twistt/TwistES) x 100, where Twistt is twist at time t and TwistES is twist at end-systole. Although peak systolic twist was not different, early diastolic LV untwisting and untwisting rate during isovolumic relaxation period was significantly delayed and reduced in parallel to the severity of LVH, as assessed by LV mass index.
CONCLUSION:The observed delayed and reduced diastolic untwisting during the isovolumic relaxation period noted in hypertensive patients with LVH may contribute towards the LV relaxation abnormality. Two-dimensional speckle tracking imaging is a novel tool which can be used for the non-invasive assessment of LV relaxation.

译文

目的: 新开发的二维超声斑点追踪成像允许测量左心室 (LV) 旋转和扭转。由于 LV 解旋主要发生在等容舒张期间,其评估反映了 LV 松弛的过程。本研究的目的是检验 LV 肥大 (LVH) 是否对 LV 解旋有不利影响,LV 解旋的异常可能成为评估 LV 松弛异常的新标记。
方法和结果: 我们获得了 49 例高血压患者的基底和心尖 LV 短轴图像。使用二维应变软件,进行时域散斑跟踪,并在每个平面上获得 LV 旋转的平均值。LV 扭转被定义为相对于基底的顶端旋转。为了调整受试者之间的心率差异,时间序列被标准化为收缩期和舒张期的百分比。LV 解旋的程度计算为收缩扭转的百分比: 解旋 = (TwistES-Twistt/TwistES) x 100, 其中 Twistt 在时间 t 处扭曲,TwistES 在收缩末期扭曲。虽然收缩期扭转峰值没有什么不同,但在等容舒张期,舒张早期 LV 解旋率和解旋率显著延迟,并与 LVH 的严重程度平行降低,由 LV 质量指数评估。
结论: 高血压 LVH 患者在等容舒张期间观察到的延迟和减少的舒张解旋可能是导致 LV 舒张异常的原因之一。二维斑点追踪成像是一种新的工具,可用于非侵入性评估 LV 松弛。

two-dimensional speckle tracking imaging

心血管 超声心动图 诊断方式
概述  :  

二维斑点追踪成像(two-dimensional speckle tracking imaging,2D-STI),又称为二维应变,是近年来一项较为先进的超声心动图技术。与组织多普勒成像技术相比,2D-STI因不受声束角度影响,在定量评价心脏功能和室壁运动时准确性较高。2D-STI是在常规灰阶图像的基础上,确定局部心肌室壁上的感兴趣区域,运用图像处理软件自动分析局部感兴趣区域的心肌组织像素的运动模式。每个感兴趣区域由20-40个像素组成。自动处理软件根据二维斑点追踪所特有的高频信号

two-dimensional   [,tu:dɪ'menʃənəl]   [,tʊdaɪ'mɛnʃənəl] 

释义   adj. 二维的;缺乏深度的

例句   One very important difference is that the retinal image is two-dimensional, whereas the enviroment is three-dimensional. 

其中非常重要的不同之处是视网膜上的是二维的,而现实世界是三维的。

 

speckle   ['spek(ə)l]   ['spɛkl] 

释义   n. 斑点,色斑

v. 用斑点做标记;弄上斑点

例句   And the displacement of speckle image reflects the distortion or displacement of objects. 

而激光散斑图像的位移可以反映出物体的位移或形变。

 

tracking   ['trækɪŋ]  

释义   n. 追踪,跟踪

v. 跟踪(tracking形式)

短语   tracking system 跟踪系统,追踪系统

tracking error 跟踪误差;循迹误差

例句   We continued tracking the plane on our radar. 

我们继续用雷达追踪那架飞机。

 

Imaging ['ɪmɪdʒɪŋ]   ['ɪmɪdʒɪŋ] 

释义   n. 成像

v. 想像(imageing形式);画的像

短语   three-dimensional imaging 三维成像

imaging sensor 成像传感器

例句   Objective To study the value of electroencephalography and magnetic resonance imaging in theearly diagnosis and prognosis of virus encephalitis. 

目的研究脑电图和磁共振成像在病毒性脑炎的早期诊断和预后评价中的价值。


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