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首页 > 医学词汇大全 > spontaneous coronary artery dissection
spontaneous coronary artery dissection

心血管

关键词心血管 疾病 冠状动脉疾病

词汇介绍

拓展阅读

解析

Spontaneous  [spɒn'teɪnɪəs]

释义   adj. 自发的;自然的;无意识的

例句   That tells us whether the change is spontaneous.

这可以告诉我们变化是否是自发的。

 

Coronary   ['kɒr(ə)n(ə)rɪ]

释义   adj. 冠的;冠状的;花冠的

例句   What limitations might affect the generalizability of these results to all patients with both diabetes and coronary disease?

怎样的限制会对所有同时患糖尿病和冠心病的患者的结果产生过程发生作用? 

 

Artery  ['ɑːtərɪ]

释义   n. 动脉;干道;主流

例句    When they are found, doctors pass a tube with a balloon into the narrowed area and inflate the balloon to compress plaque deposits against the side of the artery.

当它们被发现后,医生通过一个软管把一个小气球进入狭小的区域并且膨胀这个气球去压缩动脉边沉淀下来的血小板。

 

Dissection  [dɪ'sekʃn]

释义   n. 解剖,切开;解剖体;详细查究

例句   Aortic dissection

主动脉夹层主动脉剥离主动脉夹层分离主动脉夹层动脉瘤

概述

冠状动脉自发夹层(spontaneous coronary artery dissection,SCAD)是一种罕见的冠状动脉疾病。该疾病最早在1931年由Pretty报道,但早期病例多基于尸检结果,随着冠状动脉影像学技术的进步,其检出率在逐渐增加。SCAD死亡率极高,约为70%-75%,其中50%直接猝死,约20%在自发夹层形成数小时内死亡。2018年AHA及ESC几乎在同一时间,分别发布了各自的SCAD专家共识文件,可见临床对于该疾病的认识在逐渐提高。SCAD的病理分型基于冠状动脉造影检

Pathogenic TSR1 Gene Variants in Patients With Spontaneous Coronary Artery Dissection复制标题

自发性冠状动脉夹层患者的致病性TSR1基因变异

发表时间:2019-07-16

影响因子:18.6

作者: Caspar Grond-Ginsbach

期刊:J. Am. Coll. Cardiol

Spontaneous coronary artery dissection (SCAD) is increasingly recognized as a cause of acute coronary syndrome. During the last several years, larger cohorts of patients have become available, facilitating the study of comorbidities and risk factors, including contributory genetic variation . Development of new genomic methods, in particular of next-generation sequencing technology, now enables the comprehensive (i.e., genome-wide) detetion of rare and common genetic variants in individual patients at rapidly decreasing costs.

译文

自发性冠状动脉夹层(SCAD)越来越被认为是急性冠状动脉综合征的原因。 在过去几年中,更多的患者群体已经可用,促进了合并症和风险因素的研究,包括促成遗传变异。 开发新的基因组方法,特别是下一代测序技术,现在能够以快速降低的成本在个体患者中进行全面(即全基因组)检测稀有和常见遗传变异。