释 义 adj. 肥厚的；过度膨胀的
同根词 hypertrophied adj.过度增大的 hypertonicity n. 高张性；过度紧张；高渗性
例 句 Objective To explore the relationship between exercise hypertension and heart damage or hypertrophic left ventricle.
cardiomyopathy 英/,kɑːdɪəʊmaɪ'ɒpəθɪ/ 美 /,kɑrdɪomaɪ'ɑpəθi/
释 义 n. a disorder (usually of unknown origin) of the heart muscle (myocardium)（尤指原发性的）心肌症，心肌病
词 源 cardio myopathy
例 句 Objective： To study the related factors of peripartum cardiomyopathy(PPCM) patients outcomes for echocardiography characteristics.
作者： Barry J. Maron
期刊：N. Engl. J. Med
Hypertrophic cardiomyopathy (HCM) is a genetic cardiomyopathy caused by mutations of the cardiac sarcomere, resulting in heterogeneous phenotypic expression with respect to the extent, location, and distribution of left ventricle (LV) wall thickening as well as a diverse clinical course including sudden death, heart failure, and stroke. The prevalence of HCM in the general population is 1 in 500 adults. Histopathology in patients with HCM reveals disorganized myocyte architecture, including hypertrophied myocytes in a disarray pattern with bizarre-shaped nuclei, abnormal intramural coronary arteries, and interstitial as well as replacement fibrosis.While many patients with HCM remain asymptomatic, it is not uncommon for patients to develop one or more of the following symptoms: dyspnea on exertion, orthopnea, paroxysmal nocturnal dyspnea, chest pain, palpitations, presyncope/syncope, postural lightheadedness, fatigue, or edema. The evaluation for HCM in an individual patient may be prompted by a family history of HCM, systolic ejection murmur, abnormal 12-lead electrocardiogram showing otherwise unexplained evidence of LV hypertrophy (LVH), and clinical symptoms including syncope. In addition to performing a comprehensive cardiac history and physical examination and an electrocardiogram (ECG) in all patients with suspected HCM, cardiac imaging to identify LVH should be performed. In the patient presenting with LVH, HCM must be distinguished from acquired causes of cardiac hypertrophy, including hypertension, aortic stenosis, and athlete's heart. Other than the dynamic subaortic (LVOT) obstruction seen in HCM, several other anatomic and physiologic abnormalities can be associated with increased pressure gradients between the LV and the aorta, including volume depletion, subaortic stenosis, and valvular aortic stenosis.