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首页 > 医学词汇大全 > Thrombectomy
Thrombectomy

心血管

关键词心血管 治疗方法 手术方法

词汇介绍

拓展阅读

解析

thrombectomy   [θrɔm'bektəmi]

        n. 血栓取出术

同根词     thrombosis n. 血栓形成

        The clinical application of catheter thrombectomy and catheter-directed thrombolysis in acute lower limb deep vein thrombosis. 导管取栓及导管接触性溶栓在急性下肢深静脉血栓中的临床应用

概述

血栓取出术主要用于去除血管中的血栓,是一种新颖的治疗方法。除了外科手术直接取出血栓外,还可在患者血管中插入导管,通过导管清除血栓来恢复血供。清除血栓后可能会置入支架或过滤器,在此过程中可能用到药物来防止进一步的凝血。主要包括外伤手术切开血管取出血栓,也可使用球囊导管取出栓子,后者可缩短手术时间,创伤较小。四肢动脉取栓适应症:原则上动脉栓塞除肢体已发生严重坏疽者或栓塞的动脉支较小,远端已建立良好的侧支,不影响血供者外,只要患者全身情况许可均应积极施行取栓术。发病时间的长短与栓子摘取术效果有密切

Aspiration thrombectomy versus stent retriever thrombectomy as frst-line approach for large vessel occlusion (COMPASS): a multicentre, randomised, open label, blinded outcome, non-inferiority trial复制标题

抽吸血栓切除术与支架取栓术作为大血管闭塞的frst线方法 (COMPASS): 一项多中心、随机、开放标签、盲法结果、非劣效性试验

发表时间:2019-03-09

影响因子:59.1

作者: Aquilla S Turk

期刊:LANCET

Multiple randomized trials have established thrombectomy as the standard of care for appropriate patients with large vessel occlusion. These trials predominantly used stent retriever devices to do a thrombectomy. It is unclear whether the benefit observed in these trials would persist if an alternative method of thrombectomy was used. As a result, established stroke guidelines specifically recommend the use of stent retrievers to the exclusion of other thrombectomy techniques A direct aspiration first pass technique is an aspiration-first approach to performing thrombectomy. This technique uses a large-bore catheter to aspirate the thrombus without initially using a stent retriever. If aspiration alone is not successful, then the large-bore catheter serves as a conduit to alternatively use a stent retriever or other means to do the thrombectomy. Findings from initial single-arm studies have suggested the direct aspiration first pass approach has promising safety and clinical efficacy, with potential improvements in time and cost compared with using a stent retriever first line approach. The technical comparability of these two approaches was also suggested when the ASTER trial, a prospective randomized trial designed to show superior angiographic outcomes with direct aspiration first pass technique compared with a stent retriever as a first line approach, failed in its primary outcome, but had similar clinical results in each arm.

译文

多项随机试验已确定血栓切除术作为适当大血管闭塞患者的护理标准。这些试验主要使用支架取出装置进行血栓切除术。目前尚不清楚如果使用另一种血栓切除术方法,这些试验中观察到的益处是否会持续存在。因此,既定的卒中指南特别建议使用支架取出器来排除其他血栓切除术技术。直接抽吸首过技术是一种先进先出的血栓切除术方法。该技术使用大口径导管来吸出血栓,而不是最初使用支架取出器。如果单独抽吸不成功,那么大口径导管用作管道以交替地使用支架取回器或其他装置进行血栓切除术。初始单臂研究的结果表明,直接抽吸一次通过方法具有良好的安全性和临床疗效,与使用支架取出器一线方法相比,可能在时间和成本上有所改善。当ASTER试验(一项前瞻性随机试验,旨在显示直接吸气一次通过技术与支架取出器作为一线方法相比,显示出优越的血管造影结果)的主要结果失败时,也提出了这两种方法的技术可比性。各组的临床结果相似。