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首页 > 医学词汇大全 > obstructive hypertrophic cardiomyopathy
obstructive hypertrophic cardiomyopathy

心血管

关键词心血管 疾病 常染色体显性遗传疾病

词汇介绍

拓展阅读

解析

Hypertrophic [,haipə'trɔfik]

释    义   adj. 肥厚的;过度膨胀的

例    句   Objective: To evaluate the clinical significance of myocardial backscatter parameters of hypertrophic myocardium in the patients with hypertension. 目的:探讨高血压病患者心肌不同肥厚程度背向散射参数变化的临床意义。

 

Obstructive 英 [əbˈstrʌktɪv]  美 [əbˈstrʌktɪv]

释    义   adj. 阻碍的;妨碍的

n. 妨碍物;障碍物

短    语   obstructive jaundice 梗阻性黄疸;阻塞性黄疸

obstructive pulmonary emphysema 阻塞性肺气肿

同根词   adj. obstructionist 阻挠议事的;蓄意阻挠的

n. obstruction 障碍;阻碍;妨碍

例    句   Both he and his father had the classic symptoms of obstructive sleep apnea. 他和他的父亲都有典型的睡眠呼吸暂停障碍的症状。

 

Cardiomyopathy 英 [,kɑːdɪəʊmaɪ'ɒpəθɪ]  美 [,kɑrdɪomaɪ'ɑpəθi]

释    义   n. (尤指原发性的)心肌症,心肌病

短    语   hypertrophic cardiomyopathy 肥厚型心肌病;肥大型心肌病

ischemic cardiomyopathy 缺血性心肌病

例    句   Prevention of dilated cardiomyopathy appears to be possible through regular supplementation with these two amino acids. 因此,定期补充服用这两种氨基酸可能可以预防扩张型心肌病的发生。


概述

肥厚型心肌病是编码心肌肌小节蛋白的基因发生变异所致的种常染色体显性遗传疾病。主要表现为向心性心肌肥厚,心室腔变小。冠状动脉管壁增厚、胶原增加,管腔变小。二尖瓣前叶瓣体宽大约25%的肥厚型心肌病存在左室流出道梗阻,即肥厚型梗阻性心肌病(obstructive hypertrophic cardiomyopathy)。临床表现1、症状:临床症状除和左室流出道狭窄程度有关外,还和心室舒张功能、心肌缺血、心律失常有关。常见的症状有胸闷、胸痛、气短、晕厥、眩晕等。严重时出现心力衰竭症状。少部

Assessment of myocardial function in obstructive hypertrophic cardiomyopathy cats with and without response to medical treatment by carvedilol.复制标题

卡维地洛对梗阻性肥厚型心肌病猫的心肌功能评估。

发表时间:2019-10-28

影响因子:1.8

作者: Ryohei Suzuki

期刊:BMC Vet. Res.

Inconsistency of treatment response in cats with obstructive hypertrophic cardiomyopathy is well recognized. We hypothesized that the difference in response to beta-blockers may be caused by myocardial functional abnormalities. This study was designed to compare myocardial function in cats with obstructive hypertrophic cardiomyopathy with and without response to beta-blockers. Twenty-one, client-owned, hypertrophic cardiomyopathy cats treated with carvedilol were analyzed. After carvedilol treatment, cats with decreased left ventricular outflow tract velocity were categorized as responders (n = 10); those exhibiting no response (no decrease in the left ventricular outflow tract velocity) were categorized as non-responders (n = 11). The cats were examined using layer-specific assessment of the myocardial function (whole, endocardial, and epicardial layers) longitudinally and circumferentially by two-dimensional speckle-tracking echocardiography, before and after carvedilol treatment.

译文

患有阻塞性肥厚性心肌病的猫的治疗反应不一致是众所周知的。 我们假设对β受体阻滞剂的反应差异可能是由心肌功能异常引起的。 这项研究旨在比较患有和不接受β受体阻滞剂的梗阻性肥厚型心肌病猫的心肌功能。 分析了二十只用卡维地洛治疗的客户拥有的肥厚型心肌病猫。 卡维地洛治疗后,左心室流出道速度降低的猫被归类为反应者(n = 10)。 那些没有反应(左心室流出道速度没有降低)的患者被归为无反应者(n = 11)。 卡维地洛治疗前后,通过二维散斑跟踪超声心动图,通过纵向和周向对心肌功能(全层,心内膜和心外膜层)的层特异性评估来检查猫。