首页 > 心血管医学词汇大全 > Pulmonary Vein Isolation
Mind the gap: Quantification of incomplete ablation patterns after pulmonary vein isolation using minimum path search.
注意差距: 使用最小路径搜索对肺静脉隔离后不完全消融模式进行量化。
Ablation gap Atrial fibrillation Distance transform Geodesic distance Minimal path search Pulmonary vein isolation
下载

摘要

Pulmonary vein isolation (PVI) is a common procedure for the treatment of atrial fibrillation (AF) since the initial trigger for AF frequently originates in the pulmonary veins. A successful isolation produces a continuous lesion (scar) completely encircling the veins that stops activation waves from propagating to the atrial body. Unfortunately, the encircling lesion is often incomplete, becoming a combination of scar and gaps of healthy tissue. These gaps are potential causes of AF recurrence, which requires a redo of the isolation procedure. Late-gadolinium enhanced cardiac magnetic resonance (LGE-CMR) is a non-invasive method that may also be used to detect gaps, but it is currently a time-consuming process, prone to high inter-observer variability. In this paper, we present a method to semi-automatically identify and quantify ablation gaps. Gap quantification is performed through minimum path search in a graph where every node is a scar patch and the edges are the geodesic distances between patches. We propose the Relative Gap Measure (RGM) to estimate the percentage of gap around a vein, which is defined as the ratio of the overall gap length and the total length of the path that encircles the vein. Additionally, an advanced version of the RGM has been developed to integrate gap quantification estimates from different scar segmentation techniques into a single figure-of-merit. Population-based statistical and regional analysis of gap distribution was performed using a standardised parcellation of the left atrium. We have evaluated our method on synthetic and clinical data from 50 AF patients who underwent PVI with radiofrequency ablation. The population-based analysis concluded that the left superior PV is more prone to lesion gaps while the left inferior PV tends to have less gaps (p 

译文

肺静脉隔离 (PVI) 是治疗心房颤动 (AF) 的常见方法,因为 AF 的初始触发通常起源于肺静脉。成功的隔离会产生一个连续的病变 (疤痕),完全包围静脉,阻止激活波传播到心房。不幸的是,环绕病变通常是不完整的,成为疤痕和健康组织间隙的组合。这些缺口是 AF 复发的潜在原因,这需要重新进行隔离手术。晚期钆增强心脏磁共振 (LGE-CMR) 是一种非侵入性的方法,也可以用于检测缺口,但目前这是一个耗时的过程, 易于高观察者间变异。在本文中,我们提出了一种半自动识别和量化消融间隙的方法。间隙量化是通过图中的最小路径搜索执行的,其中每个节点是一个 scar 块,边缘是块之间的测地线距离。我们提出了相对间隙测量 (RGM) 来估计静脉周围间隙的百分比, 它被定义为总间隙长度和环绕静脉的路径总长度的比率。此外,RGM 的高级版本已经被开发出来,以将来自不同 scar 分割技术的间隙量化估计整合到一个单一的优点中。使用标准化的左心房分区进行基于人群的间隙分布统计和区域分析。我们对 50 例接受 PVI 射频消融治疗的 AF 患者的合成和临床数据进行了评估。基于人群的分析得出结论,左侧上 PV 更容易出现病变间隙,而左侧下 PV 更容易出现较小间隙 (p  

Pulmonary Vein Isolation

心血管 治疗心房颤动 治疗方法
概述  :  

肺静脉隔离(pulmonaryveinisolation, PVI)是经导管消融治疗心房颤动最重要的核心技术之一,是通过导管消融肺静脉开口部或开口周围的心房壁,从而阻断肺静脉和心房之间的电学联系的一种消融方法,已被证实能够祛除肺静脉肌袖的触发效应,迷走神经则可能是联系肺静脉隔离与电重构的中间环节,即肺静脉隔离能够削弱迷走神经对窦房结的调节作用。PVI不仅阻断了房颤的触发病灶,也可能改变了房颤赖以维持的物质基础。主要方法①Lasso电极标测下的节段性肺静脉电隔离;②超声球囊消融肺静脉口部;③C

Pulmonary 英 /ˈpʌlmənəri/ 美 /ˈpʌlməneri/ 

释    义   adj. 肺的;有肺的;肺状的

短    语   pulmonary edema 肺水肿;肺气肿;小儿肺水肿;高山肺水肿

pulmonary sequestration 肺隔离症;肺分离;隔离肺;游离肺

pulmonary hypertension 肺动脉高压;肺高压;肺高血压;肺高压症

pulmonary function 肺功能;脉冲振荡;肺通气功能;肺的作用

例    句   In workplace settings sulfuric acid mists lead to pulmonary fibrosis, and some havesuggested lung cancer as another outcome. 在工厂设施中,硫酸尘雾导致肺纤维化,一些人已经表示肺癌是它的另一后果。

 

Vein 英 /veɪn/ 美 /veɪn/ 

释    义   n. 血管;叶脉;[地质] 岩脉;纹理;翅脉;性情

vt. 使成脉络;象脉络般分布于

n. (Vein)人名;(英)维因;(塞)魏因

短    语   femoral vein 股静脉

emissary vein 导静脉

medial vein 中脉

small vein 小静脉

同根词   adj.veinal 静脉的;矿脉的;翅脉的

例    句   Each vein of mine throbs with devotion. 我的每条血管为热爱而跳动。

 

Isolation 英 /ˌaɪsəˈleɪʃn/ 美 /ˌaɪsəˈleɪʃn/ 

释    义   n. 隔离;孤立;[电] 绝缘;[化学] 离析

短    语   Isolation room 隔离室;拒却室;断绝室

isolation valve 隔离阀;隔离活门;隔离阀

sexual isolation 性隔离;性隔绝;性别隔离

good isolation 封闭稳定;关闭不变;封锁不乱

isolation medium 分离培养基;绝缘介质

例    句   This time, however, it was accompanied by social isolation. 然而这一次,它是伴随着社会的孤立。


请扫描右侧二维码,免费查看词汇专业知识背景