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首页 > 医学词汇大全 > Silent myocardial ischemia
Silent myocardial ischemia

心血管

关键词心血管 疾病 心肌缺血

词汇介绍

拓展阅读

解析

Silent [ˈsaɪlənt]

释义   n. (印、巴)茜郎特(人名)

adj. (silent) 沉默的;寂静的;无记载的

n. (silent) 无声电影

例句   But I decided that if I kept silent it would go on for years and no one would do anything about it.

但是我下了决心,如果我保持沉默的话,这样的事情将持续几年,没有人会做任何事。

 

Myocardial 英 [,maɪəʊ'kɑːdɪəl] 美 [,maɪə'kɑrdɪəl]

释义   adj. 心肌的

n. 心肌衰弱

例句   Objective To evaluate the value of echocardiography in the diagnosis of acute myocardial infarction and its complications.

目的评价超声心动图在急性心肌梗死及其并发症诊断中的应用价值。

 

Ischemia 英 [is'ki:miə] 美 [ɪs'kimɪə]

释义   n. [内科] 局部缺血

例句   It is very important that surgery is done on patients who have been properly evaluated, in terms of evaluating them for ischemia.

非常重要的一点是只有那些经过恰当评估,尤其是对缺血情况的评估的患者可以接受手术。


概述

心肌缺血是指心脏的血液灌注减少,导致心脏的供氧减少,心肌能量代谢不正常,不能支持心脏正常工作的一种病理状态。无症状性心肌缺血(SMI)又称无痛性或隐匿型冠状动脉粥样硬化性心脏病,是指患者无心绞痛或心肌缺血相关主观症状,而经检查发现有客观证据的一过性心肌缺血。可引起心肌代谢改变、心电活动异常和心肌收缩与舒张功能障碍。发生心肌缺血后为何无症状?要理解心肌缺血无症状的机制,首先要了解心肌缺血所引起的病生理变化。一般而言,心肌缺血的病生理改变有一定的规律:冠脉狭窄或闭塞→局部心肌缺血→舒张功能异常→

Prognostic Value of Human Peripheral Monocyte Subsets for Future Coronary Events in Patients Without Significant Coronary Artery Stenosis复制标题

人外周单核细胞亚群对无明显冠状动脉狭窄患者未来冠状动脉事件的预测价值

发表时间:2019-09-11

影响因子:3.0

作者: Manabu Kashiwagi

期刊:Circ. J.

We enrolled 271 patients who were suspected to have either stable angina pectoris or silent myocardial ischemia and underwent coronary angiography (CAG). Two monocyte subsets (CD14+CD16− and CD14+CD16+) were measured by flow cytometry. Patients who did not undergo coronary artery revascularization at initial CAG were followed as the medical therapy group, which included 136 patients among whom 15 had future coronary events. The frequency of CD14+CD16+ monocytes was significantly higher in patients who had future coronary events than in those who did not (P<0.01). Furthermore, the frequencies of CD14+CD16+ monocyte were not significantly different between patients who had future coronary events and those who underwent coronary revascularization at initial CAG (P<0.33). Multivariate analysis revealed that the frequency of CD14+CD16+ monocytes was an independent predictor for future coronary events (P<0.01).

译文

我们招募了271名怀疑患有稳定型心绞痛或无症状性心肌缺血并接受了冠状动脉造影(CAG)的患者。 通过流式细胞仪测量两个单核细胞亚群(CD14 + CD16-和CD14 + CD16 +)。 在初始CAG时未进行冠状动脉血运重建的患者被作为药物治疗组,其中包括136例患者,其中15例将来发生冠心病。 有未来冠心病事件的患者中CD14 + CD16 +单核细胞的频率显着高于无冠状动脉事件的患者(P <0.01)。 此外,CD14 + CD16 +单核细胞的频率在有未来冠心病事件的患者和在初始CAG时进行冠脉血运重建的患者之间无显着差异(P <0.33)。 多因素分析表明,CD14 + CD16 +单核细胞的频率是未来冠心病事件的独立预测因子(P <0.01)。