Wolff-Parkinson-White syndrome death, sudden ventricular fibrillation
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摘要

BACKGROUND:The management of Wolff-Parkinson-White is based on the distinction between asymptomatic and symptomatic presentations, but evidence is limited in the asymptomatic population.
METHODS AND RESULTS:The Wolff-Parkinson-White registry was an 8-year prospective study of either symptomatic or asymptomatic Wolff-Parkinson-White patients referred to our Arrhythmology Department for evaluation or ablation. Inclusion criteria were a baseline electrophysiological testing with or without radiofrequency catheter ablation (RFA). Primary end points were the percentage of patients who experienced ventricular fibrillation (VF) or potentially malignant arrhythmias and risk factors. Among 2169 enrolled patients, 1001 (550 asymptomatic) did not undergo RFA (no-RFA group) and 1168 (206 asymptomatic) underwent ablation (RFA group). There were no differences in clinical and electrophysiological characteristics between the 2 groups except for symptoms. In the no-RFA group, VF occurred in 1.5% of patients, virtually exclusively (13 of 15) in children (median age, 11 years), and was associated with a short accessory pathway antegrade refractory period (P

译文

背景: Wolff-Parkinson-White 的治疗是基于无症状和有症状表现之间的区别,但是在无症状人群中证据有限。
方法和结果: Wolff-Parkinson-White 注册表是一项为期 8 年的前瞻性研究,研究对象是有症状或无症状的 Wolff-Parkinson-White 患者,他们转介到我们的心律失常科进行评估或消融。纳入标准是基线电生理测试,包括或不包括射频导管消融 (RFA)。主要终点是经历心室颤动 (VF) 或潜在恶性心律失常的患者的百分比和危险因素。在 2169 名登记的患者中,1001 (550 无症状) 没有接受 RFA (无 RFA 组),1168 (206 无症状) 接受了消融 (RFA 组)。除症状外,两组在临床和电生理特征方面无差异。在无 RFA 组中,VF 发生在 1.5% 的患者中,几乎完全发生在儿童 (中位年龄,11 岁) 中 (15 例中的 13 例), 并且与短的辅助通路顺行不应期相关 (P

wolff-parkinson-white syndrome

心血管 WPW 疾病
概述  :  

预激综合征(WPW)是指正常心脏房室传导系统外,存在附加传导旁路,在心房冲动沿着正常的传导系统下传尚未到达心室之前,部分或全部由附加旁路激动心室,而易发生室上性心动过速的一种综合征。连接心房和心室之间者,称为房室旁路或Kent束,Kent束可位于房室环的任何部位。除Kent束外,尚有三种较少见的旁路:①房-希束;②结室纤维;③分支室纤维。这些解剖联系构成各自不尽相同的心电图表现。诊断(一)症状预激综合征本身不引起临床症状,但常可发生严重心律失常,或与其他疾病并存时有增加猝死的危险。预激常并发

wolff-parkinson-white syndrome

释义   预激综合征

例句   Wolff-Parkinson-White (WPW) syndrome is the abnormality of the atrioventricularconduction, and the conduction accessory pathway (AP) is its anatomic basis. 

预激综合征是一种房室传导异常,房室旁道的存在是其发生的解剖学基础。


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