释 义 n. 沙丁氨醇，羟甲叔丁肾上腺素；舒喘灵，舒喘宁
例 句 Observe the effect of combined inhalation therapy of salbutamol and Ipratropium Bromide on children with acute asthma episode. 观察沙丁胺醇、溴化异丙托品联合吸入在儿童哮喘急性发作治疗中的疗效。
作者： Brinkman P
期刊：Eur. Respir. J.
Asthma is a heterogeneous condition, characterised by chronic inflammation of the airways, typically managed with inhaled bronchodilators and corticosteroids. In case of uncontrolled asthma, oral corticosteroids (OCSs) are often prescribed. Good adherence and inhalation technique are associated with improved outcomes, however it is difficult to monitor appropriate drug intake and effectiveness in individual patients. Exhaled breath contains thousands of volatile organic compounds (VOCs) that reflect changes in the body's chemistry, and may be useful for monitoring drug pharmacokinetics and pharmacodynamics. We aimed to investigate the association of exhaled VOCs in severe asthma patients from the U-BIOPRED cohort (by gas chromatography-time-of-flight-mass spectrometry) with urinary levels of salbutamol and oral corticosteroids (OCS) (by liquid chromatography-high resolution mass spectrometry).