释 义 n. 脱氢皮质醇，泼尼松龙（一种糖皮质激素）
例 句 Of 687 children included in the intent-to-treat analysis, 343 were in the prednisolone group and 344 in the placebo group. 参与治疗意向分析的687名儿童中，泼尼松龙组343名，安慰剂组344名。
释 义 n. [有化] 醋酸盐
同根词 acetose adj. 醋一样酸的；制造醋的；醋酸的
acetin n. [食品] 醋精；[生化] 乙酸甘油酯；甘油醋酸酯
例 句 Measure the peak area for acetate. 测出醋酸盐的峰面积。
作者： Daniel J. Ham
Duchenne muscular dystrophy (DMD) is an X-linked genetic disease characterized by progressive muscle wasting and weakness and premature death. Glucocorticoids (e.g. prednisolone) remain the only drugs with a favorable impact on DMD patients, but not without side effects. We have demonstrated that glycine preserves muscle in various wasting models. Since glycine effectively suppresses the activity of pro-inflammatory macrophages, we investigated the potential of glycine treatment to ameliorate the dystrophic pathology. Dystrophic mdx and dystrophin-utrophin null (dko) mice were treated with glycine or L-alanine (amino acid control) for up to 15 weeks and voluntary running distance (a quality of life marker and strong correlate of lifespan in dko mice) and muscle morphology were assessed. Glycine increased voluntary running distance in mdx mice by 90% (P < 0.05) after 2 weeks and by 60% (P < 0.01) in dko mice co-treated with prednisolone over an 8 week treatment period. Glycine treatment attenuated fibrotic deposition in the diaphragm by 28% (P < 0.05) after 10 weeks in mdx mice and by 22% (P < 0.02) after 14 weeks in dko mice.