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词汇介绍
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解析
bronchography /brɔŋ'kɔɡrəfi/
释 义 n. [特医] 支气管造影(术)
例 句 Bronchiectasis were demonstrated in 18 cases with 55 segments on CCT, the lesion detecting rate of CCT was lower than both bronchography and HRCT(P<0 05). 常规CT有18例发现病变,检出病变肺段数为55个,其病变检出率明显低于HRCT和支气管造影术。
概述
Dual antibiotics for bronchiectasis复制标题
双抗生素治疗支气管扩张
发表时间:2018-06-11
影响因子:7.8
作者: Felix Lambert M.
期刊:Cochrane Database Syst Rev
Bronchiectasis is a chronic respiratory disease characterised by abnormal and irreversible dilatation of the smaller airways and associated with a mortality rate greater than twice that of the general population. Antibiotics serve as front-line therapy for managing bacterial load, but their use is weighed against the development of antibiotic resistance. Dual antibiotic therapy has the potential to suppress infection from multiple strains of bacteria, leading to more successful treatment of exacerbations, reduced symptoms, and improved quality of life. Further evidence is required on the efficacy of dual antibiotics in terms of management of exacerbations and extent of antibiotic resistance. We searched for randomised controlled trials comparing dual antibiotics versus a single antibiotic for short-term (< 4 weeks) or long-term management of bronchiectasis diagnosed in adults and/or children by bronchography, plain film chest radiography, or high-resolution computed tomography. Primary outcomes included exacerbations, length of hospitalisation, and serious adverse events. Secondary outcomes were response rates, emergence of resistance to antibiotics, systemic markers of infection, sputum volume and purulence, measures of lung function, adverse events/effects, deaths, exercise capacity, and health-related quality of life. We did not apply outcome measures as selection criteria.
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