释 义 n. 对乙酰氨基酚；[药] 醋氨酚；退热净；扑热息痛（一种替代阿司匹林的解热镇痛药）
同根词 acetamide n. [有化] 乙酰胺
acetanilide n.[药] 乙酰苯胺；退热冰，退热剂
例 句 There have been no reports of interactions between this product and ibuprofen or acetaminophen. 没有报告显示本品和布洛芬或是退热净产品有相互作用。
作者： Ralf Weiskirchen
There are also some limitations in experiments conducted in primary hepatocytes. In culture, these parenchymal cells lack the contact to non-parenchymal cells and are usually exposed to highly artificial media in which numerous alterations in regard to gene expression and oxidative stress will affect the sensitivity to drugs such as APAP (Jaeschke et al., 2014). Moreover, hepatic injury caused by acetaminophen is dependent upon conversion to a toxic and reactive metabolite (N-acetyl-p-benzoquinone imine, NAPQI) (McGill and Jaeschke, 2013), which depletes hepatic GSH, binds to proteins, and causes severe damage to the liver. Therefore, any intervention that blocks NAPQI formation will also prevent downstream effects, including inflammation. The data presented by the authors shows that Montelukast impacts NAPQI formation. Thus, the major and potentially more important mechanism of protection is inhibition of acetaminophen bioactivation, not inhibition of JNK signaling or inflammation. Therefore, the reduction in inflammation, for example, is likely a secondary effect of the protection.