期刊出版原始研究结果(由编辑和评论请求)的与疾病相关的标记过程的识别是否病理损伤不可分割的一部分。疾病标记可能是基因的宿主因素诱发的疾病或发生细胞表面标记、酶或其他组件,在改变形式,不正常或异常组织浓度分布。这个杂志的目的是提供一个论坛,用于出版物处理原始观测在这发展领域的任何方面一般主题包括:识别新的遗传或非遗传标记(如细胞表面抗原,血清蛋白质,内部细胞外酶,cytogenic标记和dna序列);人口研究的新的和现有的标记,旨在阐明正态分布的信息以及在疾病状态;了解现有标记的扩增;家庭研究疾病的标记;新技术识别和/或隔离的重要的分子标记;使用单克隆抗体分子结构的定义与疾病相关的标记;抵抗疾病异常识别DNA通过DNA重组技术,基因克隆和DNA限制性内切酶片段多态性;识别标记识别肿瘤细胞恶性转化

The journal publishes original research findings (and reviews solicited by the Editor) on the subject of the identification of markers associated with the disease processes whether or not they are an integral part of the pathological lesion. The disease markers may be a genetic host factor predisposing to the disease or the occurrence of cell-surface markers, enzymes or other components, either in altered forms, abnormal concentrations or with abnormal tissue distribution. This journal is designed to provide a forum for publications dealing with original observations in this developing field on any aspect of the general topic including: Identification of new genetic or non-genetic markers (e.g., cell-surface antigens, serum proteins, intra- and extra-cellular enzymes, cytogenic markers and DNA-sequences); Population studies of new and existing markers, designed to elucidate information on their normal distribution as well as that in disease states; Amplification of knowledge about existing markers; Family studies of markers in disease; New techniques for identification and/or isolation of important marker molecules; Use of monoclonal antibodies for the definition of molecular structures associated with disease markers; Identification of disease-associated abnormalities in DNA using recombinant DNA techniques, gene-cloning and DNA restriction enzyme fragment polymorphisms; Identification of markers identifying malignantly transformed neoplastic cells