摘要

We present autopsy findings of a 22-year-old man who developed chest pain 5 days after the first dose of the BNT162b2 mRNA vaccine and died 7 hours later. Histological examination of the heart revealed isolated atrial myocarditis, with neutrophil and histiocyte predominance. Immunohistochemical C4d staining revealed scattered single-cell necrosis of myocytes which was not accompanied by inflammatory infiltrates. Extensive contraction band necrosis was observed in the atria and ventricles. There was no evidence of microthrombosis or infection in the heart and other organs. The primary cause of death was determined to be myocarditis, causally-associated with the BNT162b2 vaccine.

关键词 Adverse Event Following ImmunizationCoronavirus Disease 19MyocarditisSudden Cardiac DeathVaccinationmRNA Vaccines

相关期刊

JOURNAL OF KOREAN MEDICAL SCIENCE

影响指数:4.496

中科院分区: 暂无

方向:医学:内科

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