Androgenetic alopecia (AGA) or female pattern hair loss (FPHL) is the most common form of hair loss in men and women. Despite its common occurrence, our understanding of the etiology of AGA and FPHL remains incomplete. As such, traditional therapies demonstrate modest efficacies and new therapies continue to be sought. Low-level light therapy (LLLT) is a relatively new technique used to promote hair growth in both men and women with AGA and FPHL. Currently, there exist several LLLT devices marketed for the treatment of alopecia, which claim to stimulate hair growth; yet marketing these devices only requires that safety, not efficacy, be established. A handful of studies have since investigated the efficacy of LLLT for alopecia with mixed results. These studies suffered from power, confounding and analysis issues which resulted in a high risk of bias in LLLT studies. Due to the paucity of well-conducted randomized controlled trials, the efficacy of LLLT devices remains unclear. Randomized controlled trials of LLLT conducted and reported according to the Consolidated Standards of Reporting Trials (CONSORT) statement would greatly increase the credibility of the evidence and clarify the ambiguity of the effectiveness of LLLT in the treatment of AGA and FPHL.

译文

:雄激素性脱发(AGA)或女性型脱发(FPHL)是男女最常见的脱发形式。尽管经常发生,但我们对AGA和FPHL病因的了解仍然不完整。因此,传统疗法显示出适度的功效,并且继续寻求新疗法。低水平光疗(LLLT)是一种相对较新的技术,用于在患有AGA和FPHL的男性和女性中促进头发生长。目前,有几种用于治疗脱发的LLLT设备已上市,它们声称可以刺激头发生长。然而,销售这些设备只需要确定安全性而不是功效。此后,一些研究调查了LLLT治疗脱发的疗效,但结果不一。这些研究存在能力,混淆和分析问题,导致LLLT研究存在偏见的高风险。由于缺乏进行良好的随机对照试验,LLLT装置的功效仍不清楚。根据《合并报告标准》(CONSORT)声明进行和报告的LLLT随机对照试验将大大提高证据的可信度,并阐明LLLT在AGA和FPHL的治疗中有效性的歧义。

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