Lysosomal and cytoplasmic fractions were prepared from rat submandibular glands for investigation of the release of lysosomal acid DNase in relation to aging. It was found that the acid DNase activity ratio for cytoplasmic/lysosomal fractions in rats aged 27 months was higher than that in three-month-old rats. The release of acid DNase from the lysosomal fraction by shaking was markedly increased in the fraction from the older animals.

译文

从大鼠下颌下腺制备溶酶体和细胞质组分,以研究溶酶体酸DNase的释放与衰老的关系。发现27个月大的大鼠的细胞质/溶酶体组分的酸性DNase活性比高于3个月大的大鼠。在老年动物的部分中,通过摇动从溶酶体部分释放的酸性DNase显着增加。

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