OBJECTIVE:This study was directed at identifying clinical features of chronic rhinosinusitis with asthma, and examining the differences of the postoperative outcomes in asthmatics and nonasthmatics. STUDY DESIGN AND SETTING:Twenty-one asthmatic and 77 nonasthmatic patients who underwent functional endoscopic sinus surgery (FESS) were entered into the study. The following six parameters were determined in asthmatic and nonasthmatic groups; the presence of allergy, previous sinus surgery, severity of preoperative rhinosinusitis symptoms, improvements in postoperative rhinosinusitis symptoms, preoperative disease extent, and postoperative endoscopic outcomes. RESULTS:Symptom scores improved significantly in both asthmatics and nonasthmatics postoperatively, and asthmatics exhibited significantly worse postoperative endoscopic outcomes compared with nonasthmatics. No difference was found in other parameters between two groups. Multivariate analysis revealed asthma continues to be an independent predictor of success. CONCLUSIONS:The present study found that chronic rhinosinusitis in asthmatics showed worse postoperative outcomes than in nonasthmatics, and every attempt should be made for the improvement of surgical results in these patients.

译文

目的:本研究旨在确定慢性鼻鼻窦炎合并哮喘的临床特征,并探讨哮喘患者和非哮喘患者的术后结局差异。
研究设计和设置:接受功能性内镜鼻窦手术(FESS)的21例哮喘患者和77例非哮喘患者进入研究。在哮喘和非哮喘组中确定了以下六个参数;过敏的存在,先前的鼻窦手术,术前鼻-鼻窦炎症状的严重程度,术后鼻-鼻窦炎症状的改善,术前疾病的程度以及术后内窥镜检查的结果。
结果:哮喘患者和非哮喘患者的症状评分均明显改善,与非哮喘患者相比,哮喘患者的术后内窥镜检查结果明显较差。两组之间其他参数无差异。多变量分析显示哮喘仍然是成功的独立预测因素。
结论:本研究发现哮喘患者的慢性鼻-鼻窦炎的术后预后较非哮喘患者差,因此应尽一切努力改善这些患者的手术效果。

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