BACKGROUND & AIMS:
:The aim of this prospective cohort study was to investigate the association between intrauterine fetal growth patterns and periodontal status in pregnant women. Fifty-three pregnant women were recruited. Periodontitis was diagnosed based on probing pocket depth and clinical attachment level. Maternal urinary 8-hydroxy-2'-deoxyguanosine levels and body mass index were recorded. Ultrasonographic measurements of the biparietal diameter (BPD), abdominal circumference (AC), and femur length (FL) were recorded, and estimated fetal weight (EFW) was calculated. In addition, approximation spline curves of BPD, AC, FL, and EFW were obtained throughout the gestation period. Recorded delivery outcomes were gestational age (GA), birth weight and length, sex, placental weight, and umbilical cord length. Forty-four participants (34.1 ± 4.9 years) were analyzed. Mean neonatal birth weight was 2906.0 ± 544.4 g. On multiple regression analysis, birth weight was related with periodontitis (standardized β = -0.21, P = 0.001). For EFW and BPD, the curves of the periodontitis group were located lower than those of the non-periodontitis group, with significant differences after 32 weeks and 20 weeks of GA, respectively. In conclusion, periodontal treatment before conception may be recommended and a good periodontal condition in the early stage of pregnancy at the latest is desirable for infant growth.
背景与目标:
: 这项前瞻性队列研究的目的是调查孕妇宫内胎儿生长模式与牙周状况之间的关系。招募了53名孕妇。根据探查袋深度和临床依附水平诊断牙周炎。记录孕妇尿8-羟基-2 '-脱氧鸟苷水平和体重指数。记录双顶径 (BPD),腹围 (AC) 和股骨长度 (FL) 的超声检查,并计算估计的胎儿体重 (EFW)。此外,在整个妊娠期获得了BPD,AC,FL和EFW的近似样条曲线。记录的分娩结局包括胎龄 (GA),出生体重和身长,性别,胎盘重量和脐带长度。分析了44名参与者 (34.1 ± 4.9岁)。新生儿平均出生体重2906.0 ± 544.4 g。多元回归分析显示,出生体重与牙周炎相关 (标准化 β = -0.21,p = 0.001)。对于EFW和BPD,牙周炎组的曲线低于非牙周炎组,分别在GA 32周和20周后具有显着差异。总之,建议在怀孕前进行牙周治疗,并且最晚在怀孕初期获得良好的牙周状况对于婴儿生长是可取的。