This paper reviews the early detection and prevention strategies which have been employed in Europe for the control of mycotoxin contamination of food in the context of a hazard analysis critical control point (HACCP) framework. The critical control points (CCPs) in the whole food chain where mycotoxins such as trichothecenes and ochratoxins are important have been identified. Ecological studies on the effect of environmental factors which are marginal for growth and mycotoxin production have been identified for Fusarium culmorum and F. graminearum (deoxynivlenol production), and for Penicillium verrucosum and Aspergillus ochraceus (ochratoxin production) in relation to cereal production and for A. carbonarius in relation to grapes and wine production (ochratoxin formation). To minimise the entry of these mycotoxins into the food chain, effective and rapid diagnostic tools are required to monitor the CCPs effectively. To this end the potential use of molecular imprinted polymers, lateral flow devices and molecular-based techniques for the rapid detection and quantification of the mycotoxigenic moulds or their toxins have also been developed.

译文

:本文回顾了在危害分析关键控制点(HACCP)框架下在欧洲用于控制食品中霉菌毒素污染的早期发现和预防策略。已经确定了在整个食物链中至关重要的控制点(CCP),其中霉菌毒素如曲霉毒素和曲霉毒素很重要。对镰刀菌和禾谷镰刀菌(脱氧萘酚生产),青霉青霉和och曲霉(och曲霉毒素生产)与谷物生产和A相关的环境因素对生长和霉菌毒素产生影响的生态研究已经确定。与葡萄和葡萄酒生产有关的碳含量(och曲毒素的形成)。为了最大程度地减少这些真菌毒素进入食物链,需要有效且快速的诊断工具来有效监控CCP。为此,还已经开发出分子印迹聚合物,侧向流动装置和基于分子的技术用于快速检测和定量产毒霉菌霉菌或其毒素的潜在用途。

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