The in vitro effects of xipamide in a concentration range of 10(-8) to 10(-2) M were investigated on various Na+ and K+ transport systems in human red blood cells. Xipamide inhibited the anion carrier or DIDS-sensitive LiCO3- -influx starting from a concentration of 10(-5) M. However, a decrease in the Na+, K+-pump and the Na+, K+-cotransport activity and a rise in the passive permeability of the cell membrane was only observed starting from a concentration of 10(-4) M xipamide.

译文

:对人红细胞中各种Na和K转运系统,研究了Xipamide在10(-8)至10(-2)M浓度范围内的体外作用。 Xipamide从10(-5)M浓度开始抑制阴离子载体或DIDS敏感的LiCO3--流入。但是,Na,K泵和Na,K-共转运活性降低,而被动吸收升高仅从浓度为10(-4)M的Xipamide开始观察到细胞膜的通透性。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录