BACKGROUND:We aimed to compare the performance of EQ-5D-3 L and howRu, which are short generic patient-reported outcome measures (PROMs), in assessing the outcome of hip and knee replacements, using the Oxford Hip Score (OHS) and the Oxford Knee Scores (OKS) for comparison. METHODS:Outcome was assessed as the difference between pre-surgery and 6-month post-surgery scores. We used a large sample from the NHS PROMs database, which used EQ-5D-3 L, and a small cohort of patients having the same operations collected by MyClinicalOutcomes (MCO), which used howRu. Both cohorts completed the OHS (hips) or the OKS (knees). RESULTS:The change (outcome) between pre-op and post-op scores as measured by howRu was greater than that measured by EQ-5D, relative to that measured by OHS or OKS. For hip replacements, the correlation for change measured by howRu and OHS was r = 0.77 (0.66-0.85). The corresponding correlation for change measured by EQ-5D Index and OHS was r = 0.64 (0.63-0.64). For knee replacements the correlation between change in howRu and OKS was r = 0.86 (0.75-0.92); between EQ-5D Index and OKS r = 0.59 (0.58-0.60). CONCLUSIONS:For hip and knee replacement, the outcome measured by howRu was more highly correlated with that measured by the condition-specific Oxford Hip and Knee Scores than were EQ-5D Index or EQ-VAS. The magnitude of change before and after surgery was also greater.

译文

背景:我们的目的是使用牛津髋关节评分(OHS)和EQ-5D-3 L和howRu(这是患者报告的简短通用结果指标(PROM))的性能进行比较,以评估髋关节和膝关节置换的结果。牛津膝盖得分(OKS)进行比较。
方法:将结果评估为术前和术后6个月得分之间的差异。我们使用了来自NHS PROMs数据库的大量样本,该样本使用了EQ-5D-3L,以及一小群通过MyClinicalOutcomes(MCO)收集的具有相同手术的患者,并使用了HowRu。两个队列都完成了OHS(臀部)或OKS(膝盖)。
结果:相对于OHS或OKS而言,由howRu衡量的术前和术后分数之间的变化(结果)大于EQ-5D的变化。对于髋关节置换,通过howRu和OHS测得的变化相关性为r = 0.77(0.66-0.85)。通过EQ-5D指数和OHS测得的变化的相应相关性是r = 0.64(0.63-0.64)。对于膝关节置换,howRu和OKS的变化之间的相关性为r = 0.86(0.75-0.92);在EQ-5D索引和OKS之间的r = 0.59(0.58-0.60)。
结论:对于髋关节和膝关节置换,与EQ-5D指数或EQ-VAS相比,通过howRu测得的结局与通过特定条件的牛津臀部和膝盖得分测得的结局具有更高的相关性。手术前后的变化幅度也更大。

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