PURPOSE OF REVIEW:Focusing on the key developments since January 2019, this review aims to inform policymakers and clinical practitioners on the latest on evolving global polio epidemiology and scientific advancements to guide strategies for eradication. RECENT FINDINGS:An upsurge in wild poliovirus type 1 cases in Pakistan and Afghanistan and an expansion of type 2 circulating vaccine-derived poliovirus transmission in multiple countries threaten the remarkable progress made over past several decades by the global eradication program. These challenges have also spurred innovation on multiple fronts, including earlier detection, enhanced environmental surveillance and safer and more affordable vaccine options. SUMMARY:A concerted effort to adapt program strategies to address context-specific challenges and continued focus on innovations to enhance detection and response capabilities will be the key to achieve and sustain eradication of all types of polioviruses.

译文

审查的目的:本次审查的重点是自2019年1月以来的主要进展,旨在向政策制定者和临床医生提供有关不断发展的全球脊髓灰质炎流行病学和科学进展的最新信息,以指导消灭策略。
最近的发现:在巴基斯坦和阿富汗,野生脊髓灰质炎病毒1型病例激增,以及在多个国家/地区传播的2型循环疫苗衍生脊髓灰质炎病毒传播的扩大,威胁了全球消灭计划在过去几十年中取得的显着进展。这些挑战也刺激了多个方面的创新,包括更早发现,增强环境监测以及更安全,更实惠的疫苗选择。
摘要:作出协调一致的努力来调整计划策略以应对特定环境的挑战,并继续关注创新以增强检测和响应能力,这将是实现和持续消除所有类型的脊髓灰质炎病毒的关键。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录